The ACI rats developed hereditary renal malformations including agenesis and hydronephrosis at moderate penetrance. During construction of a variety of congenic strains based on ACI/Mna (ACI), BUF/Mna (BUF), and WKY/NCrj (WKY) rats, we found that the renal malformations were significantly suppressed by introgression of a segment of chromosome 13 of BUF rats containing Pur1 locus. It is plausibl...

abstract background and purpose:the elderly resident of sari sanatorium is vulnerable in terms of nutrition. this study has been conducted to investigate the nutritive condition of the elderly resident of sari sanatorium in 2011. materials and methods:the method of the present study is periodic and descriptive type. the 104 elderly were studied. the samples’ anthropometric indices were measured...

background: nutrition is an important determinant of health in elderly and nutritional assessment is necessary for development of treatment protocols. the study aimed to evaluate nutritional status using multidimensional assessment in elderly. methods: one hundred fourteen subjects (76 men and 64 women) from elderly residence house in kermanshah, western iran were studied. data was collected us...

Objective: Due to the increase in elderly population, there is an chronic diseases, infections, depression , and nutritional problems as well a decrease cognitive abilities. This study aimed investigate effects of status, symptoms demographic characteristics on dementia population. Materials Methods: cross-sectional analytic which took place between first day April June 2018 three family health...

The aim of this trial was to evaluate the efficacy of a mandibular advancement appliance (MAA) for obstructive sleep apnoea (OSA). Ninety-three patients with OSA and a mean apnoea-hypopnoea index (AHI) of 34.7 were centrally randomised into three, parallel groups: (a) MAA; (b) mandibular non-advancement appliance (MNA); and (c) no intervention. The appliances were custom made, in one piece. The...

INTRODUCTION Mean nuclear area of 10 nuclei (MNA-10), mitotic activity index (MAI) and Ki-67 are highly reproducible and can be routinely used as adjuncts to histopathological grading in classifying tumors. Assays of these biomarkers are non-invasive, rapid, easy to perform, more objective and accurate, with high sensitivity and specificity, and correlate well with tumor grade. MATERIAL AND M...

Neuroblastomas (NBs) exhibit heterogeneity and show clinically significant prognosis classified by genetic alterations. Among prognostic genes or genome factors, MYCN amplification (MNA) is the most established genomic marker of poor prognosis in patients with NB. However, the prognostic classification of more than 60% of patients without MNA has yet to be clarified. In this study, the applicat...

In recent decades, three generations of thiomers have been developed with the main purpose obtaining enhanced interactions mucosal tissues. Therefore, many different types thiolated ligands generated and attached to polymeric backbones. The aim this study was synthesize all directly compare their properties regarding mucus penetration mucoadhesion. Starting from pectin, unprotected thiomer pect...

The size of nuclei in histological preparations from excised breast tumors is predictive of patient outcome (large nuclei indicate poor outcome). Pathologists take into account nuclear size when performing breast cancer grading. In addition, the mean nuclear area (MNA) has been shown to have independent prognostic value. The straightforward approach to measuring nuclear size is by performing nu...

BACKGROUND Malnutrition is prevalent in elderly populations. Recommended methods of nutritional screening are often too complicated and time-consuming for routine application in frail, very old, hospitalized patients. OBJECTIVE Our aims were to identify risk factors for development of malnutrition in very old hospitalized patients and to evaluate the total Mini Nutritional Assessment (MNA) sc...