background: metabolic syndrome (mets) is a prevalent disorder in pediatric age groups, described by a combination of genetic and environmental factors. sterol regulatory element‑binding transcription factor 1 (srebf‑1) induces the expression of a family of genes involved in fatty acid synthesis. moreover, dysregulation of mir‑33b, which is located within the intron 17 of the srebf‑1 gene, disru...

epidermal growth factor (egf) is a polypeptide molecule, with important functions in epithelial growth and wound repair. it exerts its effects on cells by binding to receptors on the cell surface. the aim of this study was to evaluate and compare salivary egf levels in patients with gingivitis and advanced periodontitis as well as in healthy controls.unstimulated salivary samples were collected...

investing in research and development spending (r&d) affects total factor productivity (tfp).recently new theories of economic growth have emphasized the relationship between r&d and tfpand also identified a number of channels through which a country’s r&d affects tfp of its tradepartner. this study seeks to estimate the effect of agricultural r&d and education spending and some...

Objective: The goal of this research was to determine the influence of 4 weeks aerobic training on gene expression of tumor necrosis factor alpha (TNF-α), hypoxia-inducible factor-1 alpha (HIF-1α) and vascular endothelial growth factor (VEGF) in the cardiac tissue of diabetic rats. Materials and Methods: In an experimental study, 30 male wistar rats were partitioned into three groups (n=10), d...

conclusions traf6 plays an important role in the onset of colon cancer; therefore, drugs targeting it may have great clinical significance in the treatment of this disease. results the positive expression rate of traf6 in tumor tissues was 66.7%, which was significantly higher than in normal paracancerous tissues (18.5%). the positive expression rate of traf6 was significantly correlated with d...

many investigators are interested in finding the new cultural systems that can support the in vitro development of pre-implantation embryos better. previous studies suggested that growth factors such as epidermal growth factor (egf) are important in pre-implantation embryo development and implantation process. on the other hand, it is very important to support post thaw development of frozen em...