نتایج جستجو برای: maintenance chemotherapy

تعداد نتایج: 257449  

2014
Ryoji Takada Tatsuya Ioka Hironari Sueyoshi Nobuko Ishida Takuo Yamai Nobuyasu Fukutake Reiko Ashida Hiroyuki Uehara Akemi Takenaka Yasuhiko Tomita Kazuhiro Katayama

2.6% of pancreatic cancer patients have the primary manifestation of gastrointestinal bleeding. It is not feasible to stop the duodenal hemorrhage caused by the pancreatic cancer infiltration. A 43-year-old woman who was diagnosed as having pancreatic cancer with multiple hepatic metastases and duodenal infiltration was administered gemcitabine and S-1 combination therapy. During the chemothera...

2015
Nicolas Andre Sylvie Cointe Vincent Barlogis Laurent Arnaud Romaric Lacroix Eddy Pasquier Françoise Dignat-George Gérard Michel Florence Sabatier

Maintenance chemotherapy is an important part of the treatment of ALL in children. It relies on the long-term oral administration of daily low-dose mercaptopurin and weekly low-dose methotrexate. Although it has been used in the clinic for decades, its mechanisms of action remain unclear. Here, we investigated different angiogenic and immune biomarkers to gain insights into the mechanisms of ac...

Journal: :Blood 1975
R M Heyn P Joo M Karon M Nesbit N Shore N Breslow J Weiner A Reed D Hammond

Children with acute lymphocytic leukemia, who were in remission after induction with prednisone and vincristine and consolidation with intravenous methotrexate, were randomized into three groups receiving (1) no further therapy, (2) BCG, and (3) chemotherapy with biweekly methotrexate and monthly prednisone and vincristine. Children continuing in remission after 8 mo on chemotherapy in group 3 ...

Journal: :Leukemia research 2012
Yuki Kagoya Yasuhito Nannya Mineo Kurokawa

We performed a meta-analysis of randomized controlled trials comparing thalidomide maintenance with other regimens after induction chemotherapy for multiple myeloma. Overall, 6 trials including 2786 patients were identified. Patients treated with thalidomide maintenance had marginally better overall survival (hazard ratio HR 0.83, P=0.07). The improvement was especially prominent in a subgroup ...

Journal: :Annals of oncology : official journal of the European Society for Medical Oncology 2014
V Polo B Besse

Four to six cycles of platinum-based chemotherapy are currently recommended for the first-line treatment of advanced non-small-cell lung cancer (NSCLC). Several studies have assessed the benefit of maintenance therapy following platinum-based first-line therapy, to improve disease control, and thus, progression-free and overall survival with minimal toxicity and maintenance or improvement of qu...

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