Bone has a capability to repair itself when it is fractured. Repair involves the generation of intermediatetissues, such as fibrous connective tissue, cartilage and woven bone, before final bone healing can occur. Theprocess of cartilage-to-bone transition (CBT) is a key for the achievement of rigid bone healing duringfracture repair. We tested this potential for elastic cartilage using a long ...

Objective- To evaluate tail vertebra as an autogenous cortical bone and cancellous bone for filling ulnarsegmental bone defect in dogs.Design- Experimental study.Animals- Eight adult mongrel dogs with an aver age age of 37.S months and average body wei ght of17.62 kg.Procedure- Th e animals were randomly divided into two groups . A bone defect (2.S-cm) was created onthe middle po rtion of the r...

Objective(s):To study the effect of low-frequency vibration on bone marrow stromal cell differentiation and potential bone repair in vivo. Materials and Methods:Forty New Zealand rabbits were randomly divided into five groups with eight rabbits in each group. For each group, bone defects were generated in the left humerus of four rabbits, and in the right humerus of the other four rabbits. To t...

context a key determinant for clinical success is the diagnosis of the bone density in a potential implant site. the percentage of bone-implant contact is related to bone density, and the axial stress contours around an implant are affected by the density of bone. evidence acquisition a number of reports have emphasized the importance of the quality of bone on the survival of dental implants. t...

leukemia is the most common childhood cancer and accounts for 30-40% of all malignancies. a retrospective review  was performed of the hospital records of 9 children, 6 boys and 3 girls, aged  from 2.5 to 15 years with all initially referred to nemazee hospital nuclear medicine center for whole body bone scanning between 2000 and 2002. bone marrow pathology established all (l1) in two and all (...

Bone is formed through the processes of endochondral and intramembranous ossification. In endochondral ossification primary mesenchymal cells differentiate to chondrocytes and then are progressively substituted by bone, while in intramembranous ossification mesenchymal stem cells (MSCs) differentiate directly into osteoblasts to form bone. The steps of osteogenic proliferation, differentiation,...

Background: Hypothyroidism is associated with dysfunction of the bone turnover with reduced osteoblastic bone formation and osteoclastic bone resorption. Mesenchymal stem cells (MSCs) secrete various factors and cytokines that may stimulate bone regeneration.  The aim of this study was to determine the effects of MSCs-conditioned medium (CM) in hypothyroidism male rats after inducing bone ...