نتایج جستجو برای: male life span

تعداد نتایج: 1076501  

Journal: :Chinese journal of sociology 2021

An individual's happiness is closely related to their family life as the institution in which they spend most of life. Capitalizing on data from 2018 China Family Panel Studies, this study investigates relationship between economic standing (measured by household income and homeownership) processes marital status childlessness), well children's characteristics gender composition children adult ...

2012
Matthieu Authier Ilham Bentaleb Aurore Ponchon Céline Martin Christophe Guinet

Identifying individual factors affecting life-span has long been of interest for biologists and demographers: how do some individuals manage to dodge the forces of mortality when the vast majority does not? Answering this question is not straightforward, partly because of the arduous task of accurately estimating longevity in wild animals, and of the statistical difficulties in correlating time...

Journal: :The journals of gerontology. Series A, Biological sciences and medical sciences 2011
Richard A Miller David E Harrison C M Astle Joseph A Baur Angela Rodriguez Boyd Rafael de Cabo Elizabeth Fernandez Kevin Flurkey Martin A Javors James F Nelson Carlos J Orihuela Scott Pletcher Zelton Dave Sharp David Sinclair Joseph W Starnes J Erby Wilkinson Nancy L Nadon Randy Strong

Rapamycin was administered in food to genetically heterogeneous mice from the age of 9 months and produced significant increases in life span, including maximum life span, at each of three test sites. Median survival was extended by an average of 10% in males and 18% in females. Rapamycin attenuated age-associated decline in spontaneous activity in males but not in females. Causes of death were...

Journal: :The journals of gerontology. Series A, Biological sciences and medical sciences 2008
Ricki J Colman T Mark Beasley David B Allison Richard Weindruch

Sarcopenia, the loss of muscle mass with normal aging, devastates quality of life-and related healthcare expenditures are enormous. The prevention or attenuation of sarcopenia would be an important medical advance. Dietary restriction (DR) is the only dietary intervention that consistently extends median and maximum life span, as well as health span in rodents. Evidence suggests that DR will ha...

Journal: :Cancer research 1984
W Lijinsky M D Reuber

N-Nitrosocimetidine, a nitroso derivative of the drug cimetidine, was given to groups of 20 male and 20 female rats in drinking water at a concentration of 0.5 mM for more than 2 years. The life span of the rats was not decreased compared with untreated control animals, and there was no significant increase in incidence of any tumor that could be attributed to the treatment. In comparison, 45% ...

Journal: :The journals of gerontology. Series A, Biological sciences and medical sciences 2008
Alexey G Nikitin Serena Navitskas Lee-Ann Nicole Gordon

Despite a considerable interest in the effect caffeine has on metazoan life span, the extent, as well as the direction, of this effect is still unclear. One of the most extensively used metazoan models in longevity studies is the fruit fly Drosophila melanogaster (1). There are a number of studies on the effect of caffeine on Drosophila, most of them conducted using natural populations. However...

Journal: :The journals of gerontology. Series A, Biological sciences and medical sciences 2010
Darlene E Berryman Edward O List Amanda J Palmer Min-Yu Chung Jacob Wright-Piekarski Ellen Lubbers Patrick O'Connor Shigeru Okada John J Kopchick

Growth hormone receptor gene-disrupted (GHR-/-) mice exhibit increased life span and adipose tissue mass. Although this obese phenotype has been reported extensively for young adult male GHR-/- mice, data for females and for other ages in either gender are lacking. Thus, the purpose of this study was to evaluate body composition longitudinally in both male and female GHR-/- mice. Results show t...

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