Reduced-intensity conditioning (RIC) regimens were initially introduced to provide allogeneic stem cell transplantation (HCT), a potentially curative procedure for myeloid malignancies, for patients who were not considered eligible for conventional myeloablative HCT either because of advanced age or excessive comorbidities. A variety of RIC regimens have been studied. The exact definition of RI...

Over the past year Helicobacter pylori has been confirmed as the most important risk factor for non-cardia gastric adenocarcinomas and gastric mucosa-associated lymphoid tissue (MALT) lymphomas. Eradication therapy has been proven to be beneficial when given prior to the development of intestinal metaplasia, but is less efficacious when administered later. However, the best data from clinical t...

Cancer is a genetic disease resulting from the mutations, either inherited or acquired, altering the normal genes to abnormal ‘oncogenes’. These in turn lead through a complicated cascade of biochemical signals to uncontrolled proliferation of the affected cells, which have the properties of autonomy (independent growth), metastasis (spread to other organs), dysplasia (altered structure of the ...

Ubiquitous Epstein-Barr virus (EBV) infects not only B cells but also T and NK cells, and is associated with various lymphoid malignancies. The spectrum of EBV-associated lymphoid malignancies is expanding from Burkitt lymphoma to the newly defined systemic EBV+ T cell lymphoproliferative disease of childhood and hydroa vacciniforme-like lymphoma. However, some EBV-associated malignancies are n...

Post-transplant malignancy is a major cause of late mortality for liver transplant recipients (LTRs). This nationwide population-based cohort study investigated the cancer type, incidence, and risk factors associated with post-transplant malignancies in 2938 Taiwanese LTRs who underwent transplantation between 1998 and 2012. Data from the National Health Insurance Research Database were extract...

Introduction: This retrospective study investigated the concurrence rate and clinical characteristics of recently developed malignancies with microscopic polyangiitis (MPA). Materials and Methods: The subjects included 42 Japanese MPA cases (16 males and 26 females) that had been newly admitted to the hospital. Recent occurrences of malignancy (defined as malignancies diagnosed upon admission a...

Abstract Small bowel malignancies are rare, though colorectal cancers common. This article reviews the current imaging recommendations for small and malignancies. Contrast-enhanced computed tomography (CT) is modality of choice diagnosis/staging/response evaluation/follow-up colonic tumors. Magnetic resonance pelvis with high-resolution T2-weighted images in sagittal, oblique axial, coronal pla...

BACKGROUND Extracorporeal life support (ECLS) in patients with hematologic malignancies is considered to have a poor prognosis. However, to date, there is only one case series reported in the literature. In this study, we compared the in-hospital survival of ECLS in patients with and without hematologic malignancies. METHODS We reviewed a total of 66 patients who underwent ECLS for treatment ...