By using the D2-40 antibody, we have observed podoplanin expression in Schwann cells and perineurial cells. Podoplanin expression has not been well characterized in peripheral nerve sheath tumors. Because neoplasms of neural crest lineage, including peripheral nerve sheath and melanocytic neoplasms, may share histologic and immunohistochemical characteristics, we evaluated podoplanin and S-100 ...

Malignant peripheral nerve sheath tumor with rhabdomyoblastic differentiation, malignant triton tumor, has a rare incidence. We report such a case in a 40-year-old male who presented with a mass over the buttock. He was a previously diagnosed case of neurofibroma in the same area. Histomorphology supported by immunostaining with S-100 protein confirmed the diagnosis. Malignant triton tumor has ...

Reference 1. Lee CS, Huh JS, Chang JW, Park JK : The early detection of recurrence of malignant peripheral nerve sheath tumor by frequent magnetic resonance imaging. J Korean Neurosurg Soc 47 : 51-54, 2010 Dear Editor In the year 2010, my colleagues and I published an article entitled “The early detection of recurrence of malignant peripheral nerve sheath tumor by frequent magnetic resonance im...

UNLABELLED Malignant schwannoma of the anterior abdominal wall nerves is extremely rare. Malignant peripheral nerve sheath tumors (MPNST) represent approximately 10% of all soft tissue sarcomas and it is found in 4% of patients with neurofibromatosis 1. We present a case of malignant schwannoma in a 28-year-old female patient with neurofibromatosis 1. She presented with a painful mass in the ri...

INTRODUCTION Malignant Triton tumor is a very rare malignant peripheral nerve sheath tumor with rhabdomyosarcomatous differentiation. Most of those tumors occur in patients with von Recklinghausen's disease or as a late complication of irradiation and commonly seen in the head, neck, extremities and trunk. CASE REPORT We reported retroperitoneal malignant Triton tumor in a 57-year-old female ...

Neurofibromatosis type 1 (NF 1) is an inherited autosomal dominant disorder with an estimated incidence of 1 in 2,500 to 3,000 live births [1]. Neurofibromas are benign peripheral nerve sheath tumors developed from the proliferation of fibroblasts and Schwann cells. Wallac [2] categorized neurofibromas into four types: cutaneous neurofibromas of the epidermis or dermis, subcutaneous neurofibrom...

Tracheal obstruction caused by cervical malignant peripheral nerve sheath tumor Satoru Kitamura1, Yuki Kataoka2, Hikaru Fukutomi3, and Naoki Nakajima4 Department of Digestive Medicine, Hyogo Cancer Center, Hyogo, Department of Respiratory Medicine, Hyogo Prefectural Amagasaki Hospital, Hyogo, Department of Radiology, Hyogo Prefectural Amagasaki Hospital, Hyogo, and Department of Pathology, Hyog...

Malignant peripheral nerve sheath tumors (MPNSTs) are rare, highly aggressive tumors capable of arising de novo or from preexisting benign neurofibromas or schwannomas. The treatment of choice is surgery. Trunk and extremities are the commonest sites involved. Malignant peripheral nerve sheath tumors are rarely encountered in head and neck region. Here, we report a patient with MPNST of lower l...

285 omas are the cavernous type, whereas vertebral hemangiomas are most frequently of the capillary type. The bony trabeculae within this tumor are thought to be the result of osteoclastic resorption and osteoblastic activity by the growing vascular tumor [5]. The treatment of choice for intraossoeus hemangioma is en bloc resection with an adequate normal bone margin, and the bony defect can be...

This is a case report of a 56-year-old male with hypertension who presented with urinary retention and bowel incontinence. CT and MRI of the abdomen and pelvis showed a large complex cystic and solid enhancing mass in the right presacral space. Pathology biopsy result showed malignant peripheral nerve sheath tumor (MPNST) with extensive necrosis. The diagnosis of MPNST is extremely difficult du...