The aim of this paper was to study the activity of liver superoxide dismutase and catalase and the concentration of liver malondialdehyde in rats intoxicated with chlorfenvinphos, an organophosphate widely used as an insecticide. The study was carried out on male Wistar rats weighing 180-230 g. The rats were divided into two groups: examined receiving oil solution of chlorfenvinphos in doses of...

BACKGROUND The aim of this study was to evaluate the plasma concentrations of malondialdehyde (MDA) and nitric oxide (NO) and the plasma activities of oxidant and antioxidant enzymes in patients with IBS. MATERIAL/METHODS A total of 36 patients with IBS were included in the study. Thirty-five healthy subjects were selected to form the control group. Superoxide dismutase (SOD), catalase (CAT),...

BACKGROUND Preeclampsia (PE) is a hypertensive disorder that occurs in 2% to 8% of pregnancies. Although numerous studies have investigated the etiology and pathophysiology of preeclampsia, the precise pathological mechanisms remain poorly understood. Hence, in the present study malondialdehyde (MDA) levels and SOD expression, and Cu and Zn concentrations and ratios were correlated with birth w...

The experiment was carried out to investigate the effect of different concentrations of salicylic acid (SA), malic acid ( MA), citric acid (CA) and sucrose (Suc) on keeping quality and vase life of Chrysanthemum cut flowers. In this study three levels of malic acid (0, 100 and 150 mg l ) and salicylic acid (0, 1.5 and 3 mM) and two levels of sucrose (0 and 3% w/v) and of citric acid (0 and 150 ...

BACKGROUND Xenobiotics may exert their toxic effects on tissues directly or after they have been metabolized. Increased reactivity of xenobiotics owing to their conversion to electrophiles, free radicals, nucleophiles and redox-active reactants may also contribute to toxicity. PURPOSE The present study attempts to investigate the possible "lipid peroxidation/free radical generation" mechanism...

AIMS The study is conducted to evaluate the immunomodulatory, cytotoxicity, and antioxidant potential of Ziziphus mauritiana (Rhamnaceae). Phytochemical analysis of Z. mauritiana revealed the presence of alkaloids, anthraquinone glycoside, cardiac glycoside, saponin, tannin, and flavonoids. METHODOLOGY The cytotoxicity of the plant Z. mauritiana was evaluated by brine shrimp lethality test. A...

BACKGROUND Testicular damage due to spermatic cord torsion may lead to infertility. It is probably because of changes in oxidative stress factors such as malondialdehyde. OBJECTIVE To investigate the protective effect of melatonin (MLT), as an antioxidant, on testicular damage induced by acute unilateral spermatic cord torsion and detorsion (T/D) in rats. MATERIALS AND METHODS In this exper...

Background: Cardiovascular disorders are a major cause of morbidity and mortality in diabetic patients. Increased vascular permeability is a hallmark of diabetic vasculopathy, and the administration of natural products with antioxidant activity could restore vascular function. Objectives: In this study, the effect of chronic treatment with sesamin on vascular permeability in rats with streptozo...

A modified screen-printed carbon electrode (SPCE) has been designed and fabricated for the determination of malondialdehyde (MDA), an important biomarker oxidative stress. Magnetic graphene oxide (MGO) was synthesized coated by a molecularly imprinted polypyrrole (MIPy) preparation novel hybrid nanomaterial ([email protected]). The nanocomposite characterized using different spectroscopic imagi...

Abstract Introduction The low blood flow in ischemic stroke reduces oxygen and glucose induces a series of reactions that produce free radicals. Free radicals can destroy cell membranes (lipid peroxidation) marked by the elevation malondialdehyde (MDA), damage deoxyribonucleic acid (DNA) showed 8-hydroxy-2’-deoxyguanosine (8-OHdG). This review aimed to assess conclude research-based study syste...