نتایج جستجو برای: mantle cell lymphomas
تعداد نتایج: 1700837 فیلتر نتایج به سال:
Lymphoid neoplasms are a very heterogeneous group of tumors with different biological characteristics and clinical evolutions. Current knowledge about these neoplasms has increased dramatically thanks to multidisciplinary research integrating data from morphological and phenotypic studies to molecular and genetic approaches. The heterogeneity in these neoplasms is due in part to the diversity o...
Minimal residual disease (MRD) was evaluated in 30 patients with follicular or mantle cell non-Hodgkin's lymphoma (NHL) undergoing an intensive treatment with high-dose sequential (HDS) chemotherapy and peripheral blood progenitor cell (PBPC) autografting. To minimize the potential tumor cell contamination, PBPC harvests were scheduled at the end of HDS pretransplant phase. All patients had adv...
BACKGROUND Non Hodgkin lymphomas are the most common lymphomas in Uganda. Recent studies from developed countries have shown differences in survival for the different immunophenotypes. Such studies are lacking in Africa where diagnosis is largely dependent on morphology alone. We report immunohistochemical and other prognostic factors in B cell non Hodgkin lymphoma patients in Kampala, Uganda. ...
In the present study, our aim was to assess the incidence of BCL-1 gene rearrangements in formalin-fixed paraffin embedded (FFPE) tissue in patients with non-Hodgkin lymphomas (NHL). The BIOMED-2 protocol was applied to assess the BCL-1 gene rearrangements in NHL patients. PCR amplification was carried out on FFPE in 100 patients with B-cell lymphoma including 89 cases with diffused large B-cel...
Genome-wide miRNA profiling of mantle cell lymphoma reveals a distinct subgroup with poor prognosis.
miRNA deregulation has been implicated in the pathogenesis of mantle cell lymphoma (MCL). Using a high-throughput quantitative real-time PCR platform, we performed miRNA profiling on cyclin D1-positive MCL (n = 30) and cyclin D1-negative MCL (n = 7) and compared them with small lymphocytic leukemia/lymphoma (n = 12), aggressive B-cell lymphomas (n = 138), normal B-cell subsets, and stromal cell...
Background: The gastrointestinal tract is the most common site of extranodal Non-Hodgkin lymphoma, accounting for 20% to 40% all lymphomas. This study aims accomplish objective: classify prevalent histopathological patterns lymphoma according WHO 2019 classification based on histopathology and immunohistochemistry. Subjects methods: A cross-sectional sampled 76 patients be examined treated at H...
Background & objective: The current study aimed to perform an immunohistochemical analysis of patterns of apoptotic and cell proliferative related protein expression in different histological grades and immune phenotypes of malignant lymphomas and other lymphoproliferative disorders Methods:This observational study was carried o...
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