A supervisory controller for discrete-event (DE) systems is presented that uses a novel matrix formulation. This matrix formulation makes it direct to write down the DE controller from standard manufacturing tools such as the bill of materials or the assembly tree. The matrices also make it straightforward to actually implement the DE controller on a manufacturing workcell for sequencing the jo...

Extended release formulation of tramadol hydrochloride (TRH) based on osmotic technology was developed and evaluated. Target release profile was selected and different variables were optimized to achieve it. Formulation variables such as the level of swellable polymer, plasticizer and the coat thickness of semipermeable membrane (SPM) were found to markedly affect drug release. TRH release was ...

Automation and flexibility are often mentioned as key concepts in modern production industry. To increase the level of flexibility, deterministic finite automata (DFA) can be used to model, specify and verify the production systems. Often, it is also desirable to optimize some production criteria, such as for example the cycle time of a manufacturing cell. In this paper, a method for automatic ...

Solid dose drugs comprise a considerable segment of the pharmaceutical market. The solid dose form can offer long shelf life, convenient drug delivery, and can be packaged into capsules, tablets, gel caps, and patches. Polymorphism is the ability of a molecule to exist in more than one stable or meta-stable crystalline state. Distinct crystalline forms commonly exhibit differences in pharmacolo...

To reduce manufacturing variation due to chemicalmechanical polishing and to improve yield, layout must be made uniform with respect to density criteria. This is achieved by layout postprocessing to add ll geometries, either at the foundry or, for better convergence of performance veri cation ows, during layout synthesis [10]. This paper proposes a new min-variation objective for the synthesis ...

This book is an outgrowth of an earlier text ‘Operations Scheduling with Applications in Manufacturing and Services’ by X. Chao and M. Pinedo from 1999. The new version has been completely reorganized and extended in several directions. As the title indicates, the application areas considered in the book can be divided into two major parts: scheduling applications and services applications. Thi...

The article addresses the issues of Supply Chain (SC) performance measurement the process of qualifying the efficiency and effectiveness of the supply chain. The aim of this study is to create a supply chain measurement framework for manufacturing industry. The research is based on a review of the current understanding of supply chain management and literature related to supply chain performanc...

The creation of small manufacturing enterprises is considered by many governments and donor agencies, as the key to economic and social development in countries regardless of development level. Furthermore, review of the literature show evidence that SMEs are understood as a source of technology development. At the same time they are vulnerable to a number of restrictions such as access to fina...