Mammography is the most widely used method to screen breast cancer. Because of its mostly manual nature, variability in mass appearance, and low signal-to-noise ratio, a significant number of breast masses are missed or misdiagnosed. In this work, we present how Convolutional Neural Networks can be used to directly classify pre-segmented breast masses in mammograms as benign or malignant, using...

Data mining, the extraction of hidden information from large databases, is to predict future trends and behaviors, allowing businesses to make proactive, knowledge-driven decisions. Data-Mining classification techniques deals with determining to which group each data instances are associated with. It can deal with a wide variety of data so that large amount of data can be involved in processing...

Motivation Tumor classification using imaging mass spectrometry (IMS) data has a high potential for future applications in pathology. Due to the complexity and size of the data, automated feature extraction and classification steps are required to fully process the data. Since mass spectra exhibit certain structural similarities to image data, deep learning may offer a promising strategy for cl...

Proteomics promises to revolutionize cancer treatment and prevention by facilitating the discovery of molecular biomarkers. Progress has been impeded, however, by the small-sample, high-dimensional nature of proteomic data. We propose the application of a Bayesian approach to address this issue in classification of proteomic profiles generated by liquid chromatography-mass spectrometry (LC-MS)....

Gabor filter bank has been successfully used for false positive reduction problem and the discrimination of benign and malignant masses in breast cancer detection. However, a generic Gabor filter bank is not adapted to multi-orientation and multi-scale texture micro-patterns present in the regions of interest (ROIs) of mammograms. There are two main optimization concerns: how many filters shoul...

In this paper we summarize some experiments we have carried out in order to classify mass spectra. First we describe the pre-processing and the features extraction we have realized using the Bioinformatics toolbox of MATLAB. Then we describe results we have obtained using feed forward neural networks trained with a classical back-propagation; to avoid reinventing the wheel, WEKA has been used f...

In this paper, we investigate an approach for classification of mammographic masses as benign or malign. This study relies on a combination of Support Vector Machine (SVM) and wavelet-based subband image decomposition. Decision making was performed in two stages as feature extraction by computing the wavelet coefficients and classification using the classifier trained on the extracted features....

MOTIVATION Modern mass spectrometry allows the determination of proteomic fingerprints of body fluids like serum, saliva or urine. These measurements can be used in many medical applications in order to diagnose the current state or predict the evolution of a disease. Recent developments in machine learning allow one to exploit such datasets, characterized by small numbers of very high-dimensio...

In this paper, we present the results of our investigation on identifying the optimal segmentor(s) from an ensemble of weak segmentors, used in a Computer-Aided Diagnosis (CADx) system which classifies suspicious masses in mammograms as benign or malignant. This is an extension of our previous work, where we used various parameter settings of image enhancement techniques to each suspicious mass...