This literature review was conducted to summarize the main points of maternal thyroid function tests, with particular attention in the first trimester of pregnancy which accompanied with significant biochemical and metabolic alteration. The evaluation of thyroid function of either hyperthyroidism and hypothyroidism should be assessed by determination of serum Thyroid Stimulating Hormone (TSH), ...

Graves’ disease complicates about 0.1-1.0% of all pregnancies [1,2]. Despite its rare occurrence in pregnant women, Graves’ disease constitutes a great therapeutic challenge. Maternal thyroid stimulating antibodies (TSAbs) cross the placenta and can overstimulate the fetal thyroid after the 20th week of gestation (WG), when fetal TSH receptors become responsive to TSH and TSAbs. On the other ha...

DIETARY IODINE INTAKE IS OBLIGATORY FOR THE PROduction of thyroid hormones. Despite substantial public health advances over the past 3 decades, iodine deficiency currently affects 1.92 billion people globally. Dietary iodine requirements are increased during pregnancy due to increased thyroid hormone production, increased renal iodine losses, and fetal iodine requirements. Dietary requirements ...

Objectives: Subclinical hypothyroidism has been defined as normal free thyroxine (FT4) with elevated thyroid stimulating hormone (TSH) levels. The aim of this study is to examine the relationship between first trimester subclinical adverse obstetric outcomes in pregnant women. Methods: This retrospective cohort was conducted by examining women who applied Gynecology Department Okmeydani Trainin...