نتایج جستجو برای: maze learning

تعداد نتایج: 607640  

Journal: :Sheng li xue bao : [Acta physiologica Sinica] 2004
Neng-Bao Liu Hui Li Xiang-Qian Liu Chen-You Sun Shao-Rong Cheng Min-Hai Zhang Shao-Chun Liu Wei-Xi Wang

The present study aimed at investigating the effects of chronic multiple stress on learning and memory functions of rats. Adult male Wistar rats were randomly divided into stressed and control groups. Rats in the stressed group were irregularly and alternately exposed to the situation of vertical revolution, sleep deprivation, noise stimulation, and night illumination 6 h per day for 6 weeks to...

F Motamedi FG Davoodi M Ghasemi N Naghdi

There are several conflicting evidences showing the effect of morphine on learning and memory processes. In the present study the effect of chronic morphine administration on passive avoidance, active avoidance and spatial learning and memory of morphine dependent male rats using Passive Avoidance shuttle box and Morris Water Maze tasks were investigated, respectively. Male rats received morphi...

2013
Noriko Kumazawa-Manita Hiroshi Hama Atsushi Miyawaki Atsushi Iriki

We previously demonstrated that degus (Octodon degus), which are a species of small caviomorph rodents, could be trained to use a T-shaped rake as a hand tool to expand accessible spaces. To elucidate the neurobiological underpinnings of this higher brain function, we compared this tool use learning task with a simple spatial (radial maze) memory task and investigated the changes that were indu...

Journal: :Prague medical report 2007
J Cendelín I Korelusová F Vozeh

Lurcher mutant mice represent a model of olivocerebellar degeneration. They suffer from cerebellar ataxia and deterioration of cognitive functions. The aim of the work was to study the effect of repetitive enforced motor training on spatial learning ability and motor coordination in adult Lurcher mutant mice of the C57BI strain. Experimental mice were trained repetitively on a rotarod. Control ...

Journal: :Behavioral neuroscience 2005
Karin Van der Borght Alinde E Wallinga Paul G M Luiten Bart J L Eggen Eddy A Van der Zee

In the current study, the authors investigated whether Morris water maze learning induces alterations in hippocampal neurogenesis or neural cell adhesion molecule (NCAM) polysialylation in the dentate gyrus. Two frequently used rat strains, Wistar and Sprague-Dawley, were trained in the spatial or the nonspatial version of the water maze. Both training paradigms did not have an effect on surviv...

2005
Nasser Naghdi Nahid Majlessi

Data on the effects of serotonin reuptake inhibitors on learning and memory processes are not consistent. In the present study, the effects of citalopram, a very potent and completely selective inhibitor of the serotonin reuptake on spatial discrimination in the T-maze and Morris water maze, were assessed in mice and/or rats. Animals received different doses of citalopram (1, 2, 4, 8 or 16 mg/k...

2003
Paloma Vicens M. Carmen Carrasco Rosa Redolat

This research aimed to evaluate the effect of nicotine treatment and prior training on a spatial learning task in differently aged NMRI male mice. In a longitudinal study, mice were randomly assigned to one of 14 experimental groups receiving different combinations of chronically injected nicotine (0.35 mg/kg) administered for 10 days (5 days before and during 5 days acquisition of task) or con...

Journal: :Brain research 2005
Richard E Hartman Jin M Lee Greg J Zipfel David F Wozniak

The 2-vessel-occlusion + hypotension (2VO + H) model of transient global cerebral ischemia results in neurodegeneration within the CA1 field of the hippocampus, but previous research has failed to demonstrate robust or reliable learning/memory deficits in rats subjected to this treatment. In the present study, sensitive behavioral protocols were developed in an effort to characterize the cognit...

2016
Huaiyu Hu Yu Liu Kevin Bampoe Yonglin He Miao Yu

Patients with type II lissencephaly, a neuronal migration disorder with ectopic neurons, suffer from severe mental retardation, including learning deficits. There is no effective therapy to prevent or correct the formation of neuronal ectopia, which is presumed to cause cognitive deficits. We hypothesized that learning deficits were not solely caused by neuronal ectopia and that postnatal gene ...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2003
Daniela Steinberger David S Reynolds Pushpindar Ferris Rachael Lincoln Susmita Datta Joanna Stanley Andrea Paterson Gerard R Dawson Jonathan Flint

Inbred strains of mice are known to differ in their performance in the Morris water maze task, a test of spatial discrimination and place navigation in rodents, but the genetic basis of individual variation in spatial learning is unknown. We have mapped genetic effects that contribute to the difference between two strains, DBA/2 and C57BL6/J, using an F2 intercross and methods to detect quantit...

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