Comparative genomic hybridization (CGH) studies have shown that chromosome 8 is a frequent target for chromosomal aberrations in breast cancer. We characterized these aberrations of chromosome 8 in 16 breast cancer cell lines (BT-474, BT-549, CAMA-1, DU-4475, MCF-7, MDA-MB134, MDA-MB-157, MDA-MB-361, MDA-MB-415, MDA-MB-436, MPE600, SK-BR-3, T-47D, UACC-812, UACC-893 and ZR-75-1) by CGH, fluores...

ABSTRACTDiazinon has a hepatotoxic effect since it is metabolized in the liver involving Kupffer cells (KCs) activation, increasing reactive oxygen species (ROS). The flavonoids contained shallot (Allium cepa L.) skin act as antioxidants neutralizing oxidative stress. This study aims to determine of ethanol extract (SSEE) on MDA level and activated KCs histopathology. total SSEE was measured us...

Phosphocreatine (PCr) is an endogenous compound containing high-energy phosphate bonds. It has been confirmed that PCr is effective in preventing and treating cardiac and renal ischemia-reperfusion injury. In this study, rat cerebral ischemia-reperfusion injury models were constructed. Apoptotic cells in the cortex region were measured by TUNEL method. Malondialdehyde (MDA) content was detected...

This article presents a model-driven approach to improve interoperability of enterprises information systems. This approach proposes to design a mediation information system (MIS) dedicated to deal with exchanged data, shared services and collaborative processes. The MIS design crosses the different abstraction layers (business, logic and technological) and exploits at each level the associated...

Software architecture decisions hinge more on non-functional requirements (NFRs) than on functional ones, since the architecture stipulates which software to build. Model-Driven Architecture (MDA) aims to automate the derivation/generation of software from high level architectural specifications, but most current MDA implementations start from software design (i.e. how to build a software piece...

Transmission assessment surveys (TAS) for lymphatic filariasis have been proposed as a platform to assess the impact of mass drug administration (MDA) on soil-transmitted helminths (STHs). This study used computer simulation and field data from pre- and post-MDA settings across Kenya to evaluate the performance and cost-effectiveness of the TAS design for STH assessment compared with alternativ...

INTRODUCTION The depletion of defensive body chemicals called antioxidants may increase the risk of complications from the most common form of diabetes mellitus. This study aims to evaluate blood serum lipid peroxidation product (malondialdehyde), an antioxidant, in non-insulin dependent male and female type 2 diabetic patients. METHODS Blood serum samples were collected from the diabetic pat...

Currently, standardized distributed simulation systems are likely to follow the High Level Architecture (HLA) standard, not only because it is widely adopted in the United States for DoD applications, but also because it can be seen as the most matured M&S standard in this domain. However, the HLA focuses on the implementation level; thus it cannot solve problems on the conceptual level, such a...

In this study, changes in malondialdehyde level (MDA), superoxide dismutase (SOD) and catalase (CAT) activity fish liver tissue were investigated by applying two doses of 2,4-dichlorophenoxyacetic acid (2,4-D) herbicide to Capoeta umbla for 72 hours. Changes MDA level, CAT SOD determined spectrophotometric methods. As a result the it was that there statistically significant increase C. exposed ...

The correlation between the blood lead (B-Pb ) levels and the values of blood pressure in hypertensive patients was investigated. Moreover, plasma levels of nitric oxide (NO), total antioxidants (TAOX) and malondialdehyde (MDA) were detected to investigate the correlations between the measured parameters and B-Pb levels in hypertensive patients. Fifty-five hypertensive patients were compared wi...