The coupling of optical emitters with a nanostructured environment is at the heart of nano- and quantum optics. We control this coupling by the lithographic positioning of a few (1-3) quantum dots (QDs) along plasmonic silver nanowires with nanoscale resolution. The fluorescence emission from the QD-nanowire systems is probed spectroscopically, by microscopic imaging and decay time measurements...

We assessed metabolic changes for darunavir/ritonavir (DRV/r) once daily (qd) versus atazanavir/ritonavir (ATV/r) qd with fixed-dose tenofovir/emtricitabine. This was a phase 4, multicenter, open-label, randomized exploratory study. Treatment-naive, HIV-1-infected adults received DRV/r 800/100 mg qd or ATV/r 300/100 mg qd, both with emtricitabine/tenofovir 200/300 mg qd. Primary end point: chan...

IDX899 is a novel nonnucleoside reverse transcriptase inhibitor (NNRTI) with potent in vitro activity against wild-type and NNRTI-resistant strains of human immunodeficiency virus type 1 (HIV-1) and with a high genetic barrier to resistance. Single rising doses of 50 and 100 (given by use of a 50-mg capsule) and 200, 400, 800, and 1,200 mg (given by use of a 200-mg capsule) of IDX899 or matchin...

The outstanding features of Quantum Dot Semiconductor Optical Amplifiers (QD-SOA’s) such as all-optical signal processing and signal regeneration are caused them are widely used in the optical communication systems. Due to the nano structure of these amplifiers, accurate design and modelling of them is a complex and challenging problem. This paper addresses design a QD-SOA. We present a novel m...

BACKGROUND The fertility performance of animals is still a mystery and the full comprehension of mammalian gametes maturation and early embryonic development remains to be elucidated. The recent development in nanotechnology offers a new opportunity for real-time study of reproductive cells in their physiological environments. As a first step toward that goal, we evaluated the effectiveness of ...

BACKGROUND/AIM The basic role of vascular endothelial growth factor (VEGF) in cancer is underscored by the approval of bevacizumab for first-line treatment of cancer patients. Recent anticancer therapeutics based on active tumor targeting by conjugating tumor-specific antibodies has become of great interest in oncology. Current progress in nanomedicine has exploited the possibility of designing...

If f is a binary word and d a positive integer, then the generalized Fibonacci cube Qd(f) is the graph obtained from the d-cube Qd by removing all the vertices that contain f as a factor, while the generalized Lucas cube Qd( ↽Ð f ) is the graph obtained from Qd by removing all the vertices that have a circulation containing f as a factor. The Fibonacci cube Γd and the Lucas cube Λd are the grap...

Generalized Fibonacci cube Qd(f) is introduced as the graph obtained from the d-cube Qd by removing all vertices that contain a given binary string f as a substring. In this notation the Fibonacci cube Γd is Qd(11). The question whether Qd(f) is an isometric subgraph of Qd is studied. Embeddable and nonembeddable infinite series are given. The question is completely solved for strings f of leng...