Nanostructured materials have shown significant potential for biomedical applications that require high loading capacity and controlled release of drugs. Nanoporous gold (np-Au), produced by an alloy corrosion process, is a promising novel material that benefits from compatibility with microfabrication, tunable pore morphology, electrical conductivity, well-established gold-thiol conjugate chem...

Nanoscale redox cycling is a powerful technique for detecting electrochemically active molecules, based on fast repetitive oxidation and reduction reactions. An ideal implementation of redox cycling sensors can be realized by nanoporous dual-electrode systems in easily accessible and scalable geometries. Here, we introduce a multi-electrode array device with highly efficient nanoporous redox cy...

We have performed first-principles density functional theory calculations, incorporated with van der Waals interactions, to study CO2 adsorption and diffusion in nanoporous solid – OMS2 (Octahedral Molecular Sieve). We found the charge, type, and mobility of a cation, accommodated in a porous OMS-2 material for structural stability, can affect not only the OMS-2 structural features but also CO2...

renal ischemia-reperfusion (ir) contributes to the development of acute renal failure (arf). oxygen free radicals are considered to be principal components involved in the pathophysiological tissue alterations observed during renal ir. the purpose of this study was to investigate the combination effect of melatonin (mel) and erythropoietin (epo), which are a potent antioxidant and anti-apoptoti...

Diquat dibromide is a moderately toxic contact herbicide belonging to the bipyridyl group of redox-active compounds that induce a strong oxidative damage. Melatonin (MEL) can protect against oxidative damage under in vivo conditions, probably through its anti-oxidative capacity and ability to induce expression of anti-oxidative enzymes. The objective of this study was to investigate effects of ...

The current research aimed to quantify melittin (MEL) in Iranian honey bee (Apis mellifera meda) venom. To this end, a liquid chromatography-electrospray ionization-ion trap tandem mass spectrometry (LC-ESI-IT-MS/MS) approach was employed. Melittin is the main toxic peptide of honey bee venom with various biological and pharmacological activities. It was extracted with...

Two-dimensional (2D) materials have been received increasing attention in various fields such as physics, material science, chemistry and engineering. In particular, the graphene-based membrane is an emerging subject mainly due to the atomic thickness, simple processing and the compatibility with other materials. In the case of water treatment, stable graphene-based laminar structures as well a...

The aim of current bone biomaterials research is to design implants that induce controlled, guided, successful, and rapid healing. Titanium implants are widely used in dental, orthopedic, and reconstructive surgery. A series of studies has indicated that cells can respond not only to the chemical properties of the biomaterial, but also, in particular, to the changes in surface topography. Nanop...

Microstructural and mechanical properties of organic surfactant templated nanoporous thin silica films have been studied by X-ray diffraction, Fourier transform infrared spectroscopy, and nanoindentation. Compared with many other porous low-k dielectrics, the self-assembled molecularly templated nanoporous silica films demonstrate better mechanical properties. This is ascribed to the presence o...

Cell adhesion, migration, and proliferation are significantly affected by the surface topography of the substrates on which the cells are cultured. Alumina is one of the most popular implant materials used in orthopedics, but few data are available concerning the cellular responses of mesenchymal stem cells (MSCs) grown on nanoporous structures. MSCs were cultured on smooth alumina substrates a...