Biologically active CAM may detrimentally interfere with chemotherapy treatment, so cancer patients require targeted, evidence-based information on chemotherapy-CAM integration consequences. The object of this study was to investigate the potential for medical doctor recommendation and patient acceptance of a purpose-designed patient educational brochure on the safe use of CAM with chemotherapy...

Results Twenty-seven percent of the respondents reported that they used CAM for at least one child in their family. Parents with higher education and income used CAM more than less educated parents and those with lower incomes. Parents who have tried CAM for themselves used it also for their children. Parents who have not vaccinated or partially vaccinated their children used CAM more than pare...

Doctors should: Honestly answer patients' direct questions about CAM and elicit information about their use of it. Establish patients' understanding of the conventional and complementary therapies, both those available to them, and those that they may already be using. Establish why the patient uses CAM, and their goals for both complementary and conventional therapies. Reflect on whether infor...

The protein ankyrin links integral membrane proteins to the spectrin-based membrane skeleton. Ankyrin is often concentrated within restricted membrane domains of polarized epithelia and neurons, but the mechanisms responsible for membrane targeting and its segregation within a continuous lipid bilayer remain unexplained. We provide evidence that neuroglian, a cell adhesion molecule related to L...

The mechanisms that govern leukocyte transmigration through the endothelium are not yet fully defined. Junctional adhesion molecule (JAM) is a newly cloned member of the immunoglobulin superfamily which is selectively concentrated at tight junctions of endothelial and epithelial cells. A blocking monoclonal antibody (BV11 mAb) directed to JAM was able to inhibit monocyte transmigration through ...

The cellular prion protein was historically characterized owing to its misfolding in prion disease. Although its physiological role remains incompletely understood, PrP(C) has emerged as an evolutionary conserved, multifaceted protein involved in a wide-range of biological processes. PrP(C) is a GPI-anchored protein targeted to the plasma membrane, in raft microdomains, where its interaction wi...

The potential relationship of cell adhesion to embryonic induction during feather formation was examined by immunohistochemical analysis of the spatiotemporal distribution of three cell-adhesion molecules (CAMs), neural CAM (N-CAM), liver CAM (L-CAM), and neuron-glia CAM (Ng-CAM), and of substrate molecules (laminin and fibronectin) in embryonic chicken skin. The N-CAM found at sites of embryon...

At that time, little was known about possible benefits and challenges of combining conventional and CAM treatments for people with MS. Therefore we initiated the MS Treatment Team Project as a pioneer project with the aim of gaining more knowledge within this field. We established an integrative team of practitioners that included 5 conventional practitioners and 5 CAM practitioners; these 10 w...