نتایج جستجو برای: mena countries

تعداد نتایج: 257312  

Journal: :BAU journal. Society, culture & human behavior 2021

Against the context of consecutive world financial crisis, this paper aims to evaluates merits market-based against bank-based financing by analyzing correlation between structure and systemic risk eleven countries within MENA region. Within study three hypotheses are tested; first, if significantly related, second, relation is non-linear relationship third one bank doesn’t contribute above thr...

Journal: :Journal of Infection in Developing Countries 2021

Introduction: Our study aims to assess the prevalence of COVID-19 in Middle East and North Africa (MENA) region. It also examine various factors that have led unequal distribution confirmed cases among different MENA countries.
 Methodology: Data was retrieved from World Health Organization situation reports issued between January 29 June 5, 2020. included numbers cumulative cases, new dea...

2016
Michele Balsamo Chandrani Mondal Guillaume Carmona Leslie M. McClain Daisy N. Riquelme Jenny Tadros Duan Ma Eliza Vasile John S. Condeelis Douglas A. Lauffenburger Frank B. Gertler

During tumor progression, alternative splicing gives rise to different Mena protein isoforms. We analyzed how Mena11a, an isoform enriched in epithelia and epithelial-like cells, affects Mena-dependent regulation of actin dynamics and cell behavior. While other Mena isoforms promote actin polymerization and drive membrane protrusion, we find that Mena11a decreases actin polymerization and growt...

Journal: :Cancer discovery 2016
Madeleine J Oudin Oliver Jonas Tatsiana Kosciuk Liliane C Broye Bruna C Guido Jeff Wyckoff Daisy Riquelme John M Lamar Sreeja B Asokan Charlie Whittaker Duanduan Ma Robert Langer Michael J Cima Kari B Wisinski Richard O Hynes Douglas A Lauffenburger Patricia J Keely James E Bear Frank B Gertler

UNLABELLED Fibronectin (FN) is a major component of the tumor microenvironment, but its role in promoting metastasis is incompletely understood. Here, we show that FN gradients elicit directional movement of breast cancer cells, in vitro and in vivo Haptotaxis on FN gradients requires direct interaction between α5β1 integrin and MENA, an actin regulator, and involves increases in focal complex ...

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