BACKGROUND Typhoid fever is one of the most important infectious diseases transmitted by contaminated food and water. This study aimed at epidemiological features of disease during the last five decades, over the period from 1962-2011. METHODS A retrospective cross-sectional study was conducted using typhoid fever national surveillance data. RESULTS The highest incidence of typhoid fever wa...

BACKGROUND Salmonella enterica serovar Typhi causes an estimated 22 million cases of typhoid fever and 216 000 deaths annually worldwide. We investigated an outbreak of unexplained febrile illnesses with neurologic findings, determined to be typhoid fever, along the Malawi-Mozambique border. METHODS The investigation included active surveillance, interviews, examinations of ill and convalesce...

Mania following or associated with medical and pharmacological conditions is well known. However there are not too many reports of mania following typhoid fever. This paper describes a mania syndrome following successfully treated typhoid fever in a young male without any past or family history of psychiatric illness or associated psychosocial stressors.

OBJECTIVE To compare the efficacy and safety of azithromycin with ofloxacin in patients with uncomplicated typhoid fever. MATERIAL AND METHODS Forty adult patients with bacteriologically or serologically diagnosed, uncomplicated typhoid fever were included from Medicine out-patient department at Government medical college, Amritsar, India. They were randomized into 2 groups of 20 patients eac...

The Typhoid Fever Surveillance in Africa Program (TSAP) was established in 2009 to fill the data void concerning invasive Salmonella disease in sub-Saharan Africa, and to specifically estimate the burden of bloodstream infections caused by the key pathogen, Salmonella enterica serovar Typhi. TSAP has achieved this ambitious target, finding high incidences of typhoid fever in both rural and urba...

While it is commonly believed that recovery from typhoid fever confers a fairly solid immunity, the older literature contains a number of reports of second attacks (1). Generally speaking, the second attack rate has been reported to range from 1 to 4 per cent, a figure compatible with (although by no means proving) the assumption that recovery leads to immunity. However, there are significantly...

Typhoid fever, a systemic disease caused by Salmonella typhi, is classically characterized by fever and abdominal symptoms. Although now considered uncommon, it seems to have re-emerged in Taiwan in recent years. We conducted a retrospective study of the clinical characteristics and microbiologic findings in 24 confirmed cases of typhoid fever treated over a 7-year period at a medical center in...

A 14 year old boy developed the syndrome of Bickerstaff's brainstem encephalitis during the course of bacteriologically proved typhoid fever. The clinical course and the results of various neurological investigations are detailed. This report adds a further manifestation to the published neuropsychiatric complications of typhoid fever.

Medical literature contains surprisingly few accounts of large series of typhoid fever in children in which such items as severity, response to therapy, complications, and relapse rates are reported in detail. The purpose of this paper is to present a study of typhoid fever in African and Indian children in Durban, and to review the relevant literature on the subject emanating from other countr...

Experimental human typhoid fever challenge was first described in 1896 by Wright, who vaccinated two men against typhoid fever and challenged one with what was then known as Salmonella typhosa. While challenge models are sometimes controversial, they offer enormous potential to study the pathogenesis of disease and to accelerate vaccine development, particularly in humanrestricted pathogens suc...