An immunoassay that detects mercuric ions in water at concentrations of 0.5 ppb and above is described. The assay utilizes a monoclonal antibody that binds specifically to mercuric ions immobilized in wells of microtiter plates. Within the range of 0.5-10 ppb mercury, the absorbance in the enzyme-linked immunosorbent assay (ELISA) is linear to the log of the mercuric ion concentration. The quan...

In the Brown Norway (BN) rat, mercuric chloride (HgCl(2)) induces a T(h)2-dominated autoimmune syndrome which includes an early phase of mast cell-dependent vasculitis. We have shown in vitro that oxidative stress up-regulates IL-4 in mast cells and predisposes to degranulation. The aim of this study was to determine whether administration of antioxidants inhibits HgCl(2)-induced early vasculit...

forty bacteria species commonly found in soil, sediments, and sewage effluent were exposed for acclimation to inorganic and organic mercury compounds using sterilized sediments as the culture medium. screening tests for the ability of microorganisms to methylate inorganic mercury were made on all 40 species after acclimation to 13.5 mg/i mercuric chloride. additional screening tests for demethy...

The aim of the study was to determine toxic effect and dynamics oxidative stress caused by mercury chloride (HgCl2) in rainbow trout (Oncorhynchus mykiss) weighing 59.43 ± 7.21 g.For this purpose, a total 40 fish 4 groups, 10 each group (n = 10), were exposed 25% 50% (137.75 μg/L 275 μg/L) LD50 for 2 7 days. To oxidative/nitrosative stress, Peroxynitrite (ONOOˉ mmol/L), Total Oxidant Level (TOS...

The aim of this study was to determine oxidative stress caused by mercury chloride (HgCl2) in rainbow trout (Oncorhynchus mykiss) liver tissue. For purpose, the LD50 value HgCl2 on determined as 551 μg/L. In study, 40 fish four groups were exposed 25% and 50% (138 276 µg/L) two subletal doses for 2 7 days, with 10 (n=10) each group. To stress; peroxynitrite (ONOO−), total oxidant level (TOS), a...

The effect of selenite administered at various time intervals after mercury treatment on the toxicity and renal content of mercuric mercury in mice was studied. A marked protective effect of selenite on growth depression and renal lesions caused by mercuric chloride was observed in mice receiving mercury and selenite simultaneously. However, growth depression was not protected by post administr...