نتایج جستجو برای: merkel cell polyomavirus

تعداد نتایج: 1686347  

2012
Rachel M. Schowalter William C. Reinhold Christopher B. Buck

Merkel Cell Polyomavirus (MCV or MCPyV) was recently discovered in an aggressive form of skin cancer known as Merkel cell carcinoma (MCC). Integration of MCV DNA into the host genome likely contributes to the development of MCC in humans. MCV infection is common and many healthy people shed MCV virions from the surface of their skin. MCV DNA has also been detected in samples from a variety of o...

2009
M J Flaig

MCPyV prevalence of 7.5% represents the MCPyV prevalence in the general population. We found almost identical numbers for the MCPyV prevalence in non-MCC tumours of sun-exposed skin. More data will be needed to prove this assumption. Nevertheless, the morphological similarities of both tumours are striking and will keep the intriguing idea of a possibly (polyoma-) virus-associated pathogenesis ...

Journal: :Thorax 2009
S S Birring I D Pavord

MCPyV prevalence of 7.5% represents the MCPyV prevalence in the general population. We found almost identical numbers for the MCPyV prevalence in non-MCC tumours of sun-exposed skin. More data will be needed to prove this assumption. Nevertheless, the morphological similarities of both tumours are striking and will keep the intriguing idea of a possibly (polyoma-) virus-associated pathogenesis ...

Journal: :International journal of cancer 2009
Masahiro Shuda Reety Arora Hyun Jin Kwun Huichen Feng Ronit Sarid María-Teresa Fernández-Figueras Yanis Tolstov Ole Gjoerup Mahesh M Mansukhani Steven H Swerdlow Preet M Chaudhary John M Kirkwood Michael A Nalesnik Jeffrey A Kant Lawrence M Weiss Patrick S Moore Yuan Chang

Merkel cell polyomavirus (MCV) is a recently discovered human virus closely related to African green monkey lymphotropic polyomavirus. MCV DNA is integrated in approximately 80% of Merkel cell carcinomas (MCC), a neuroendocrine skin cancer linked to lymphoid malignancies such as chronic lymphocytic leukemia (CLL). To assess MCV infection and its association with human diseases, we developed a m...

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