background: erythropoietin (epo) is a glycoprotein hormone function to regulate the production of red blood cells. deficiency of epo is known to cause anemia in chronically infected renal patients and they require regular blood transfusion. availability of recombinant epo has eliminated the need for blood transfusion and now it is extensively used for the treatment of anemia. glycosylation of e...

objective: cell vital function has correlation with mechanical loadings that cell experiences. here, effects of in-vitro combined cyclic-static stretch on proliferation of human mesenchymal stem cell (hmsc) were evaluated. materials and methods: hmscs were cultured on gelatin coated elastic membranes, and exposed to stretch loading. four different regimes of cyclic, static, combined cyclic-sta...

intraosseous squamous cell carcinoma is a rare type of squamous cell carcinoma that requires accurate and early diagnose which is important due to its invasive feature. this article presents a rare case report on intraosseous carcinoma in a 33-year-old patient. the case was a 33-year-old man who was referred to oral disease department of babol college of dentistry complaining of chin pain. in t...

in this center, from 1991 to 2002, 89 chronic myelogenous leukemic (cml) patients, age ranging between 8-48 years with a median age of 29, underwent hematopoietic stem cell transplantation. eighty-eight patients were in the first chronic phase of disease. twenty-three patients received bone marrow transplantation (bmt) and 66 patients received peripheral blood stem cell transplantations (pbsct)...

conclusions according to our results, silymarin injection caused significant differentiation of mscs to neurons and neuroglia that could be a promising approach for treating a variety of brain injuries. results expression of cd29 and cd90 markers that are characteristic of bmmscs were confirmed by flow cytometry experiments. the data demonstrated that proliferation and number of progenitor cell...

langerhans cell histiocytosis (lch) is the most common type of childhood histiocytic disorder with an incidence of 0.2 to 1 per 100,000 children under the age of 15 years (1). the clinical picture of lch varies from single system (s-s)bone or skin disease to multi-system disease (m-s) (2). we report a neonate with disseminated papulonodular eruption containing mononuclear cd1a and s100 positive...

the t helper 17 (th17) cells have been suggested to have osteoclast activating effects while t helper 2 (th2) cells are considered to have an osteoprotective role in periodontitis. this study was to compare the markers of th17 cells (rorc2 and il-17 genes) with that of th2 cells (il-4 and gata-3 genes) between healthy and periodontitis tissues.the samples were obtained from patients with period...

purpose: to report the early results of transplantation of autologous limbal stem cell cultivated on amniotic membrane in total limbal stem cell deficiency. methods: four eye of 4 patients with total unilateral stem cell deficiency secondary to severe chemical or thermal burn were included. stem cell deficiency was confirmed with impression cytology in all cases. under topical anesthesia, a sma...

results there was a significant difference in prevalence of ebv presence between patients and controls. the ebv was found by rt-pcr in 19 (63.33%) out of 30 patients and only in eight (26.7%) of 30 control samples. the p = 0.004, was calculated using chi-square test (or: 4.75; 95% ci: 1.58 ‒ 14.25). conclusions our study is the first investigation performed on patients with lch and its possible...