OBJECTIVES To investigate the prevalence of tooth loss and different prosthetic rehabilitations among Iranian adults, as well as the potential determinants of tooth loss. METHODS In a cross-sectional community-based study conducted among 8094 Iranian adults living in Isfahan province, a self-administered questionnaire was used to assess epidemiologic features of tooth loss. RESULTS Thirty-t...

A new diagnostic indicator of FDG PET scan abnormality, based on age-adjusted t statistics and an automated voxel-based procedure, is presented and validated in a large data set comprising 110 normal controls and 395 patients with probable Alzheimer's disease (AD) that were studied in eight participating centers. The effect of differences in spatial resolution of PET scanners was minimized effe...

It has been observed repeatedly that risk factors for cardiovascular diseases tend to co-occur within individuals (1, 2). Typically, disturbances of glucose metabolism, dyslipidemias, central obesity, and elevated blood pressure are among the metabolic and hemodynamic components considered. These observations have been made both on the individual level and at the population level as association...

The significance of metabolic syndrome in association with cardiovascular diseases has triggered extensive debate, and the number of medical reports in this area is increasing exponentially. One of several controversial points is whether the 5 components (elevated glucose, higher triglyceride, lowered highdensity lipoprotein [HDL] cholesterol, central obesity, and hypertension) of metabolic syn...

INTRODUCTION In Central and Eastern European countries, cardiovascular disorders (CVD) in middle age are much more common than in Western Europe, and it is imperative to understand the causes underlying this excess disease burden. The metabolic syndrome comprises a constellation of metabolic abnormalities that increase the risk of cardiovascular disease. METHODS Data were obtained by structur...

OBJECTIVES We determine the prevalence of the metabolic syndrome in an urban population of Zanjan, a province located to the west of Tehran. METHODS Randomly selected adults >20 years were studied using stratified sampling. Target study sample was 2941 (1396 males and 1545 females). Metabolic syndrome was diagnosed using Adult Treatment Panel-III (ATP-III) guidelines when any three of the fol...

BACKGROUND Phenylalanine and tyrosine are precursor amino acids required for the synthesis of dopamine, the main neurotransmitter implicated in the neurobiology of schizophrenia. Inflammation, increasingly implicated in schizophrenia, can impair the function of the enzyme Phenylalanine hydroxylase (PAH; which catalyzes the conversion of phenylalanine to tyrosine) and thus lead to elevated pheny...

BACKGROUND AND PURPOSE Abnormal hypometabolism is common in the brain parenchyma surrounding developmental venous anomalies (DVAs), although the degree of DVA-associated hypometabolism (DVAAh) has not been quantitatively analyzed. In this study, we demonstrate a simple method for the measurement of DVAAh and test the hypothesis that DVAs are associated with a quantifiable decrement in metabolic...

We aim to investigate the risk of incident arterial stiffness according metabolically healthy obese (MHO) phenotype in Chinese population. 37,180 participants with at least one-time measurement branchial-ankle pulse wave velocity (baPWV) were included cross-sectional analysis, and 16,236 repeated baPWV during follow-ups longitudinal study. Cross-classification body mass index (BMI) categories m...