A genome-wide association study showed that the tagging single nucleotide polymorphism (SNP) rs7566605 in the insulin-induced gene 2 (INSIG2) was associated with obesity. Attempts to replicate this result in different populations have produced inconsistent findings. We aimed to study the association between the rs7566605 SNP with obesity and other metabolic parameters in Malaysian Malays. Anthr...

At calving time, the cows were monitored and blood samples were taken from jugular vein of 38 cows with parturient paresis and 38 healthy ones. The levels of calcium, phosphorus, magnesium, sodium, potassium, chloride, glucose, triglyceride, cholesterol, albumin, globulin and A/G ratio were assessed to find the correlation between the degree of hypocalcemia and other parameters. According to ca...

This paper demonstrates methods for the online optimization of assistive robotic devices such as powered prostheses, orthoses and exoskeletons. Our algorithms estimate the value of a physiological objective in real-time (with a body "in-the-loop") and use this information to identify optimal device parameters. To handle sensor data that are noisy and dynamically delayed, we rely on a combinatio...

the present study deals with the oral supplementation with (50, 100 and 150 ?g/ml) synergetic effect of potassium and magnesium chloride on the fat body glycogen, protein, total lipids and haemolymph trehalose, protein of fifth instar larvae of bombyx mori l (lepidoptera: bombycidae). the observed parameters significantly increased in all the treated groups when compared with those of the corre...

The aim of this study was to evaluate the oxidative stress and metabolic activities of nurses working day and night shifts. Intensive care unit (ICU) (n=70) and ordinary service (OS) nurses (n=70) were enrolled in the study. Just before and the end of the shifts, blood samples were obtained to measure the participants' oxidative stress parameters. Metabolic activities were analyzed using the Se...

Dietary restriction interventions are effective for weight loss and reduction of chronic disease risk. Unfortunately, most people tend to regain much of this lost weight within one year after intervention. While some studies suggest that minor degrees of weight regain have no effect on metabolic disease risk parameters, other studies demonstrate a complete reversal in metabolic benefits. In lig...

BACKGROUND Patients with schizophrenia suffer high rates of metabolic derangements on some antipsychotic medications that predispose them to cardiovascular diseases. Keeping this fact in mind, we planned this open-label study to see the effect on various metabolic parameters after switching stable schizophrenia subjects, who had developed metabolic syndrome on olanzapine, to aripiprazole. MET...

Pharmacokinetic studies are used to discover the fate of drug in the body. Knowledge of the route of removal, metabolic paths and the degree of efficiency are vital informations for the right dosage, which protects the body against potential drug toxicity (1ñ5). Amoxicillin (AMX) is a semisynthetic penicillin (2, 5, 6ñ8) belonging to aminopenicillin group with a wide range of bactericidal activ...