نتایج جستجو برای: metabolic pathways

تعداد نتایج: 438817  

Clostridium ljungdahlii is a strictly anaerobic acetogene known for its ability to ferment a wide variety of substrates to ethanol and acetate. This bacterium presents a complex anaerobic metabolism including the acetogenic and solventogenic phases. In this study, the effect of various carbon sources on triggering the metabolic shift toward solventogenesis was considered. The bacterium was grow...

Objective(s): Many cancer cells show significant resistance to drugs that kill drug sensitive cancer cells and non-tumor cells and such resistance might be a consequence of the difference in metabolism. Therefore, studying the metabolism of drug resistant cancer cells and comparison with drug sensitive and normal cell lines is the objective of this research. Material and Methods:Metabolism of c...

Journal: :iranian journal of basic medical sciences 0
ehsan motamedian biotechnology group, department of chemical engineering, tarbiat modares university, tehran, iran. drug design and bioinformatics group, medical biotechnology department, biotechnology research center, pasteur institute of iran, tehran, iran ghazaleh ghavami drug design and bioinformatics group, medical biotechnology department, biotechnology research center, pasteur institute of iran, tehran, iran. eastern mediterranean health genomics and biotechnology network (emgen), tehran, iran soroush sardari drug design and bioinformatics group, medical biotechnology department, biotechnology research center, pasteur institute of iran, tehran, iran

objective(s): many cancer cells show significant resistance to drugs that kill drug sensitive cancer cells and non-tumor cells and such resistance might be a consequence of the difference in metabolism. therefore, studying the metabolism of drug resistant cancer cells and comparison with drug sensitive and normal cell lines is the objective of this research. material and methods:metabolism of c...

2016
Jinping Gu Xiaomin Hu Wei Shao Tianhai Ji Wensheng Yang Huiqin Zhuo Zeyu Jin Huiying Huang Jiacheng Chen Caihua Huang Donghai Lin

Gastric cancer (GC) is one of the most malignant tumors with a poor prognosis. Alterations in metabolic pathways are inextricably linked to GC progression. However, the underlying molecular mechanisms remain elusive. We performed NMR-based metabolomic analysis of sera derived from a rat model of gastric carcinogenesis, revealed significantly altered metabolic pathways correlated with the progre...

Journal: :Health Information Science and Systems 2013

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