The effect of blending a small amount high-density polyethylene (HDPE) on molecular entanglements during melt-drawing ultrahigh-molecular-weight (UHMW-PE) was investigated in this study. UHMW-PE powders with HDPE added and bimodal MW distribution were synthesized by reactor blending. In situ wide-angle X-ray diffraction small-angle scattering measurements UHMW-PE/HDPE films performed to evaluat...

In this study, 20 metallocene-based compounds comprising extensive structural diversity were synthesized and evaluated as carbonic anhydrase (CA, EC 4.2.1.1) inhibitors. These compounds proved moderate to good CA inhibitors in vitro, with several compounds displaying selectivity for cancer-associated isozymes CA IX and CA XII compared to off-target CA I and CA II. Compound 6 was the most potent...