1. Propylene oxide reacts with DNA in aqueous buffer solution at about neutral pH to yield two principal products, identified as 7-(2-hydroxypropyl)guanine and 3-(2-hydroxypropyl)adenine, which hydrolyse out of the alkylated DNA at neutral pH values at 37 degrees C. 2. These products were obtained in quantity by reactions between propylene oxide and guanosine or adenine respectively. 3. The rea...

Single intraperitoneal injections (of 0.5, 1.0, and 2.0 ml per kilogram body weight) of a solution of sodium pentobarbital (50 mg/mI, in propylene glycol, 40 ml/100 ml) elevated rat serum triglyceride values obtained by the semi-automated fluorometric method of Kessler and Lederer. Increases of 267, 619, and 813%, respectively, were noted within 5 mm. Liver triglycerides and other major lipid f...

The thermal oxidation of propane in the temperature range 350-425oC was studied in order to elucidate the role of higher aldehydes as degenerate branching intermediates in the oxidation of hydrocarbons. In the slow combustion of propane, the high yield of propylene and methanol as the primary products, the formation of hydrogen peroxide, carbon monoxide, carbon dioxide, formaldehyde and steam a...

The paths of nucleophilic fluoroalkylation reaction of propylene oxide with PhSO2CYF (Y = F, H, and PhSO2, respectively) in the gas phase and in Et2O solvent were studied theoretically. The nucleophilic fluoroalkylation of propylene oxide with fluorinated carbanions was probed by comparison of the reactivities (phenylsulfonyl)monofluoromethyl anion (PhSO2CHF), the (phenylsulfonyl)difluoromethyl...

The possibility to implement both the exhaustive dehydrogenation of aqueous methanol to hydrogen and CO2 and the reverse reaction, the hydrogenation of CO2 to methanol and water, may pave the way to a methanol based economy as part of a promising renewable energy system. Recently, homogeneous catalytic systems have been reported which are able to promote either one or the other of the two react...

A pilot-scale fluidized bed reactor was built and used to study and gain a better understanding of the propylene polymerization process at conditions similar to those of industrial fluidized-bed reactors. Propylene polymerization reaction was carried out continuously in the reactor and dynamic temperatures, and propylene and hydrogen concentrations data were collected. Simulated dynamic profile...

Experimental drugs and/or plant extracts are often dissolved in solvents, including propylene glycol. Nevertheless, there is evidence for psychoactive properties of this alcohol. In this study we found that in the hole-board test 10% propylene glycol did not modify the head-dipping behavior. However, 30% propylene glycol induced an increase in the number of head-dips (46.92 +/- 2.37 compared to...

The composition of narrow distribution poly ethylene oxide-propylene oxide copolymer (Mw ~ 8700 Da) was studied using matrix assisted laser desorption ionization (MALDI) mass spectrometry. The ethylene oxide-propylene oxide copolymer produced oligomers separated by 14 Da. The average resolving power over the entire spectrum was 28,000. Approximately 448 isotopically resolved peaks representing ...

Partial molar volumes of copper sulphate and zinc sulphate have been determined in water and binary aqueous mixtures of propylene glycol (2,4,6 and 8% by weight of propylene glycol) at 303.15 K with the help of density measurements. Effect of temperature on the partial molar volumes was also analysed for these salts in water and binary aqueous mixtures of propylene glycol. Results obtained have...

Oxidation of functioning copper has restricted its applicability as a catalyst for commercially important epoxidation of propylene to form propylene oxide. Here, we report that steady-state selectivity in propylene epoxidation on copper (Cu) nanoparticles increases sharply when the catalyst is illuminated with visible light. The selectivity increase is accompanied by light-induced reduction of ...