Lack of data on safety of herbal medicines have endangered human health and life. The present study evaluated the genotoxic and mutagenic effect of Kalanchoe laciniata to access the safety and usefulness of the medicinal plant. Aqua-methanolic and n-hexane extracts of K. laciniata were evaluated for the genotoxic potential using Ames assay and cytotoxicity was evaluated using MTT assay. Ames as...

The present study was undertaken to assess in vitro antioxidant and immunomodulatory activity for methanolic extract of Ficus benghalensis Linn. aerial roots (MEFB). Antioxidant activity of (MEFB)was evaluated by reducing power assay and hydrogen peroxide assay. Immunomodulatory activity was evaluated for specific and non-specific immune response by using in vitro assays as plaque forming cell ...

Methanolic and aqueous extracts of Dendrophthoe falcata Linn. leaves which belongs to the Loranthaceae family, were evaluated through DPPH (1, 1-diphenyl -2-picryl-hydrazyl), antilipid peroxidation and nitric oxide scavenging methods to assess the antioxidant activity. Methanolic and aqueous extracts of Dendrophthoe falcata leaves were also evaluated for their anti-inflammatory activity by carr...

significant dropping of infectious disease is owned greatly to antibiotic development industry. due to prevalence of drug resistance organisms alongside with other problems, scientists are focusing on medicinal plants. medicinal plants and their antimicrobial components are attractive alternatives for antibiotics. in the present project, the antimicrobial effects of methanolic extract and fract...

The anticandidal activity of the methanolic extract of Wedelia chinensis leave was studied and tested against four pathogenic Candida albicans strains of clinical isolates. The extract exhibited favorable anticandidal activity with the zones of inhibition between 18.00 ± 0.10 to 20.00 ± 0.17 mm and minimum inhibition concentration (MIC) values between 3.13 and 6.25 mg/mL. The time-kill studied ...

Background: Alchemilla abyssinica is a plant widely used in traditional medicine. Its wide use among the community plus already established scientific evidences for medicinal values of other Alchemilla species provided good ground for this investigation. Methods: In this research, CHCl3/EtoAc 1:1 extract of dried aerial parts of Alchemilla abyssinica, methanolic extract of the CHCl3/ EtoAc resi...

Radical Scavenging capacity Abstract: In-vitro antioxidant activity of methanolic extract of Rhinacanthus nasutus leaves was determined by DPPH free radical scavenging assay and Reducing Power assays. Ascorbic acid was used as standard and positive control for both the analysis. All the analysis was made with the use of UV-Visible Spectrophotometer. The methanolic extract of Rhinacanthus nasutu...

We aimed to investigate the apoptotic effects of the methanolic extract of Dorema glabrum seed on WEHI-164, cancerous cells in comparison with L929, normal cells and compared them with the cytotoxic effects of Taxol. So, MTT test and DNA fragmentation assay were performed on cultured and treated cells. Also electrophoresis which was followed by immunoblotting was done to survey the production o...

Objective: The present study was designed to evaluate adaptogenic activity of methanolic and aqueous extract of roots of Mikania micrantha Kunth in Wistar albino rats using different experimental models such as Anoxia stress tolerance, swimming endurance and immobilisation stress. Methods: The plant was subjected to preliminary phytochemical screening. The parameters like anoxia stress toleranc...

Objective: The aim of this research work was to study the in vitro anti-inflammatory activity of the methanolic leaf extract of Litsea quinqueflora (Dennst.) Suresh. Methods: Methanolic extract of the powdered leaves was subjected to preliminary phytochemical screening as per the standard protocols of Trease and Evans. In vitro anti-inflammatory activity was evaluated by HRBC membrane stabiliza...