During a survey of methylotrophic yeasts in natural habitats in Hungary, the yeast community associated with the exudates of white poplar (Populus alba) was found to be unique among the tree exudates hitherto investigated. Nineteen methanol-assimilating yeast strains representing an undescribed ascomycetous species were isolated from tree exudates of P. alba collected at different locations in ...

Mutants of the methylotrophic actinomycete Amycolaropsis methanolica unable to grow on methanol as carbon source were isolated and characterized. Mutants specifically affected in methanol utilization were deficient in formaldehyde assimilation. Mutants blocked in the first step of primary alcohol oxidation (Cl-C4) had lost activity of the tetrazolium-dependent alcohol dehydrogenase, a three-com...

Methanol bioconversion toward chemical production can be helpful for carbon neutrality. Here metabolic engineering an industrial methylotrophic yeast Ogataea polymorpha was conducted overproduction of 3-hydroxypropionate (3-HP), important platform chemical, which used special chemicals including acrylamide, acrylic acid, 1,3-propanediol, as well biodegradable plastics. We developed several stra...