Background Severe aortic stenosis (AS) induces diffuse interstitial myocardial fibrosis (MF). CMR late gadolinium enhancement (LGE) technique is useful to detect focal MF. The amount of MF is associated with worse long-term prognosis after aortic valve replacement surgery (AVR). Measurements of T1 relaxation times before and after gadolinium administration allow determination of myocardial extr...

This paper presents a fuzzy multi-attribute decision-making algorithm for evaluating flexibility in a manufacturing system development. This evaluation problem is formulated as a multi-attribute decision-making model in a fuzzy environment and solved by a fusion method based on the MEOWA operators. While evaluating the degree of manufacturing flexibility (MF), one may find the need for improvin...

Lymphatic filariasis is a major tropical disease caused by the parasite Brugia malayi. Microfilariae (Mf) circulate in the peripheral blood for 2-3 hours in synchronisation with maximal feeding of the mosquito vector. When absent from the peripheral blood, Mf sequester in the capillaries of the lungs. Mf are therefore in close contact with vascular endothelial cells (EC) and may induce EC immun...

PURPOSE To assess the accuracy of templating in total hip arthroplasty (THA). METHODS Anteroposterior pelvic radiographs of 20 men and 33 women aged 17 to 80 (mean, 60) years who underwent uncemented THA of the right (n=24) and left (n=29) sides using a single prosthesis were reviewed. A 30-mm-diameter scaling ball was placed between the patient's legs for calculating the magnification factor...

Despite consensus in focus on form (FOF) instruction over the facilitative role of noticing, controversy has not quelled over ways of directing EFL learners’ attention towards formal features via implicit techniques like input-enhancement or explicit metacognitive feedback and interactive peer-editing on the output they produce. This quasi-experimental study investigated the impact of input enh...

Mycosis Fungoides (MF) is the most common type of Cutaneous T-Cell Lymphoma (CTCL) and represents nearly 50% of all primary cutaneous lymphomas [1]. MF is characterized by an epidermotropic skin infiltrate of atypical CD4+ phenotype lymphocytes. In a minority of MF cases, the atypical infiltrate is CD8 positive. The later form of CTCL generally follows a rapid, aggressive clinical course [2]. H...

Magnetic field as ecological factor has influence on all living beings. The aim of this study was to determine if extremely low frequency magnetic field (ELF-MF, 50 Hz, 0.5 mT) affects oxidative stress in the brain of gerbils submitted to 10-min global cerebral ischemia. After occlusion of both carotid arteries, 3-month-old gerbils were continuously exposed to ELF-MF for 7 days. Nitric oxide an...

Calorie restriction (CR) is a dietary regimen that supports healthy aging. In this study, we investigated the systemic and liver-specific responses caused by a diet switch to a medium-fat (MF) diet in 24-month-old lifelong, CR-exposed mice. This study aimed to increase the knowledge base on dietary alterations of gerontological relevance. Nine-week-old C57BL/6J mice were exposed either to a con...

Pathologic diagnosis requires tissue fixation for histologic and immunohistologic analysis, and formalin is routinely used for this. The disadvantage of this fixative is its inability to preserve nucleic acids. Pathologic tumor diagnosis requires extensive molecular analyses, for which formalin fixation may be not adequate. Recently, an alcohol-based fixative (molecular fixative, MF) was descri...

An experimentally induced wound made in a confluent monolayer culture of porcine thoracic aortic endothelial cells (ECs) was studied 22 hours after wounding using 7-nitrobenz-2-oxa-1,3-diazole (NBD) phallacidin and immunofluorescence microscopy to localize actin and myosin containing microfilament (MF) bundles. ECs extending from the wound edge back toward the confluent monolayer showed a speci...