In our current study, phytochemical analysis and antibacterial activity of leaf extracts T. parthenium were assessed. Qualitative screening was carried using standard procedures quantitative for estimation total phenolic content (TPC) determined by spectrophotometric method. The accomplished disc diffusion assay, determination minimum inhibitory concentration (MIC) bactericidal (MBC) against tw...

Background: Chromolaena odorata plant is a weed that grows abundantly in various places, including geothermal areas. Its leaves contain chemical compounds such as alkaloids, flavonoids, steroids, and tannins can function antibacterials.Objectives: The study aims to determine the Minimum Inhibitory Concentration (MIC) Bactericidal (MBC) of ethanol extract grown area Ie Seum Aceh Besar against St...

Highlights:1. Typhoid fever, a major health problem for developing countries, requires alternative therapy to reduce drug resistance.2. A. bilimbi, native plant of Indonesia, has antibacterial potential, which is effective against S. typhi in vitro. AbstractIntroduction: Some plants Indonesia have potential effects on and medication. This study aimed determine the effect Averrhoa bilimbi (A. bi...

Staphylococcus aureus and Pseudomonas aeruginosa are part of the human microbiota and are also important bacterial pathogens, for which therapeutic options are lacking nowadays. The combined administration of corticosteroids and antimicrobials is commonly used in the treatment of infectious diseases to control inflammatory processes and to minimize potential toxicity of antimicrobials, avoiding...

INTRODUCTION Tuberculosis continues to be a devastating public health problem. Many communities in Uganda use medicinal plants to treat various infections, including respiratory tract infections. There are claims that some can treat tuberculosis. Verifying some of these claims could lead to discovery of lead compounds for development of a TB drug. METHODS Chloroform and methanol extracts of L...

A novel and time-saving method for assessing bactericidal activities of beta-lactam antibiotics on agar plates is described. Minimal inhibitory concentrations (MICs) were determined by the agar dilution method. A potent beta-lactamase solution was sprayed onto the plates to inactivate the antibiotic. After further incubation at 37 degrees C overnight, the minimal concentration at which no visib...

The pharmacokinetics and pharmacodynamics of two multiple-dose regimens of piperacillin-tazobactam (3.375 g every 6 h and 4.5 g every 8 h) were evaluated at steady state for 12 healthy adult volunteers. Inhibitory and bactericidal activities for the two regimens were determined with five American Type Culture Collection (ATCC) organisms (Escherichia coli, Staphylococcus aureus, Klebsiella pneum...

Nature is an unexplored reservoir of novel phytopharmaceuticals. Since biofilm-related oral diseases often correlate with antibiotic resistance, plant-derived antimicrobial agents could enhance existing treatment options. Therefore, the rationale of the present report was to examine the antimicrobial impact of Mediterranean natural extracts on oral microorganisms. Five different extracts from O...

OBJECTIVES The antibacterial activity of Coffea canephora extract was evaluated in vitro against Streptococcus mutans and Streptococcus sobrinus. The viability of planktonic cells was analysed by susceptibility tests (MIC and MBC) and time-kill assays. The effect of the extract on dental demineralisation was also investigated. METHODS Primary 1st molar fragments (n=24) were inoculated with a ...