mancozeb, a fungicide of a manganese-zinc ethylenebisdithio-carbamate (ebdc), was administered by gavage at doses of 200, 400, 600 and 800 mg/kg/day to female virgin mice for 30 days. the mice were autopsied on 31st day. mice were also treated with similar doses for a period of 30 days and the treatment was withdrawn for a further period of 30 days for reversible study. the mice were autopsied ...

background: the present study deals with the effect of helminthic infection as nematode parasite like aspiculuris tetraptera on the haematological parameters of infected and vaccinated mice. methods: totally 15 mice were used. five mice were used for positive control, 5 mice used for nega­tive control and 5 mice used for experiment. the hematological parameters were studied viz. rbc, hb, and se...

background and objectives: glycoprotein 96 is the primary chaperone of the endoplasmic reticulum. immunization with it induced potent cytotoxic t lymphocyte responses to intracellular bacteria. s. typhimurium is a facultative intracellular bacterium and acquired resistance against this bacterium mainly depends on activity of cytotoxic t cells. this study aimed to evaluate the capacity of glycop...

objective: oximes are important materials in organic chemistry. synparamethyl benzaldehyde oxime (toloaldoxime) is structurally similar to other oximes, hence we have studied its effects on the neonatal and adult female balb/c mice reproductive systems in order to provide a platform for future studies on the production of female contraceptive drugs. materials and methods: in experimental study,...

background: cutaneous leishmaniasis caused by l. major is an important public health problem in endemic areas. the aim of this study was to explore the therapeutic effect of microwave and or infrared radiation in the treatment of lesion induced in balb/c mice by l. major inoculation. methods: the footpad lesion was induced in balb/c mice by inoculation of l. major promastigotes subcutaneously. ...

introduction: the mechanisms of hepatic encephalopathy are not fully understood. moreover, there is no comprehensive data concerning the effects of nitric oxide (no) system on anxiolytic-like behaviors induced by bile duct ligation (bdl). methods: male mice weighing 25-30 g were used and anxiety-like behaviors were tested using hole-board task. results: the data indicated that cholestasis incre...

background: magnetized water has made many improvements in industry, agriculture and medicine. however its utilization in medicine still remains controversial. objective:  in this study we aimed to investigate the effects of magnetized water on height of epithelial cells in pre-implantation stage endometrium and fallopian tube and number of corpus lutea in female mice. materials and methods:  e...

background: caffeine increases the camp production that stimulates spermatozoa movement. caffeine is also used for induction of in vitro acrosome reaction in mammalian spermatozoa, an important step in achieving fertilization. objective: the aim of this study was to assess the effect of caffeine on sperm's motility, vitality and laboratory fertilization rates in mouse in two t6 and m16 media. m...

it is now well documented that interferon gamma (ifn-γ) is the indispensable cytokine for inducing protective immunity against experimental and human cutaneous leishmaniaisis. the importance of ifn-γ receptor (ifn-γr) has also been studied. in the present study, we made attempts to find out whether l. major infection is able to alter the expression of ifn-γr in vivo. in addition, we studied the...