BACKGROUND Microalbuminuria is known as a risk factor for hypertension. Recently it was suggested that urine albumin-to-creatinine ratio (UACR), even within the normal range, can be associated with hypertension, but the temporal relationship between normal range UACR and hypertension was not confirmed. Therefore the aim of this study was to verify an association between normal range UACR and th...

Diabetes mellitus is the main cause of all diseases. The prevalence diabetes cases inCentral Java Province in 2019 was 652,822 cases. Cases Brebes Regency are quite high with18,724 patients. increases constantly if it not treated properly and will lead tocomplications. most frequent complication causing a decrease kidney function which ischaracterized by albuminuria. Prolanis aims to prevent co...

Diabetic retinopathy is a common microvascular complication of diabetes mellitus and one the leading causes acquired blindness. Microalbuminuria reflects pathophysiological state vascular dysfunction organ damage. It noticed that rise in urinary albumin excretion seen early phase diabetic retinopathy. The concordance microalbuminuria has been well reported type 1 diabetes; however, for 2 diabet...

This study presents an integrated microfluidic chip for non-immunologically determining the concentrations of albumin in clinical urine samples. This microchip integrates membrane-type micromixers and a fan-shaped micropump capable of simultaneously and precisely delivering assay reagents to react with 6 urine samples in one single operation. The experimental results show that the coefficient o...

We examined sex differences in kidney mineral concentrations and urinary albumin excretion in rats given feed containing various phosphorus (P) levels. With feed that was 0.6%, 0.9%, 1.2%, and 1.5% P, kidney calcium and P concentrations were higher in female rats than in male rats. With 1.2% or 1.5% P, urinary albumin excretion was higher in the female rats. The sex of the animal affected the k...

A simple, specific and sensitive sequential injection analysis (SIA) system based on non-immunoassay fluorescent detection has been developed for the determination of urinary albumin. The specific binding of the dye Albumin Blue 580 (AB 580) to albumin in urine generated high emission fluorescent signals. The excitation and emission wavelengths were set at 590 and 610 nm, respectively. The anal...

BACKGROUND Gross albuminuria is associated with increased stroke risk, but it is unclear whether stroke incidence varies by level of albuminuria. We meta-analyzed prospective cohort studies to investigate the impact of various albuminuria levels and continuous urinary albumin excretion (UAE) change on stroke risk. METHODS Systematic search for studies reporting quantitative estimates of the m...

PURPOSE There have been few studies on gender difference in the impact of a urine albumin-to-creatinine ratio (UACR) within the normal range on the risk of hypertension. We evaluated whether the association between the UACR below the microalbuminuria range and the incident risk of hypertension is different between men and women. MATERIALS AND METHODS A total of 1173 individuals (442 men and 7...

BACKGROUND Chronic kidney disease is a growing public health problem worldwide. Previous studies have identified several predictors for renal function decline. However, these studies used a single measurement of these risk factors. Therefore, the aim of this study was to investigate whether besides the baseline values of these risk factors, changes in risk factors are associated with subsequent...