Jos Boekhorst,1,2,3 Greer Wilson4 and Roland J. Siezen1,2,3* TI Food and Nutrition, 6700AN Wageningen, the Netherlands. NIZO food research, 6710BA Ede, the Netherlands. Netherlands Bioinformatics Centre and Centre for Molecular and Biomolecular Informatics, NCMLS, Radboud University Nijmegen Medical Centre, 6500HB Nijmegen, the Netherlands. Science Consultant, Bowlespark 30, 6701DS Wageningen, ...

Proteomics belongs to the group of so called “ omics ” technologies that are preferentially exploited for the global analysis of temporal or conditional alterations in gene expression, on either the gene or protein level. Proteomics is focused on proteins and provides information about their abundances, post translational modifi cations, localization and mutual interactions. Current proteomic p...

Carbon and nitrogen present in residual water streams can be converted into microbial protein used as animal feed aquaculture. While is thought to more environmentally sustainable when compared proteins made from fish residues or plants, nothing known about how it performs an absolute sustainability perspective, relative planetary boundaries. Here, a systems-oriented analysis using life cycle a...

Candida species represent a major fungal threat for human health. Within the genus, yeast albicans is most frequently incriminated during episodes of candidiasis or candidemia. Biofilm formation used by C. to produce microbial community that important in an infectious context. The cell wall, superficial cellular compartment, paramount importance regarding establishment biofilms. wall contains p...

Background: Milk is one of the most nutritious foods providing a variety of proteins, fats, minerals, and vitamins needed to maintain, grow, and develop the body. The aim of this study was to assess microbial and chemical adulterants of raw cow milk collected from dairy farms of Hlabisa villages, KwaZulu-Natal Province, South Africa. Methods: A total of 68 raw cow milk samples were obtained fr...

SUMMARY mimicMe is a web server for prediction and analysis of host-like proteins (mimics) encoded by microbial pathogens. Users select a host species and any set of pathogen and control proteomes (bacterial, fungal, protozoan or viral) and mimicMe reports host-like proteins that are unique to or enriched among pathogens. Additional server features include visualization of structural similariti...

Innovations in next-generation sequencing technology have introduced new avenues in microbial studies through "omics" approaches. This technology has considerably augmented the knowledge of the microbial world without isolation prior to their identification. With an enormous volume of bacterial "omics" data, considerable attempts have been recently invested to improve an insight into virosphere...

Transgenic or genetically modified plants possess novel genes that impart beneficial characteristics such as herbicide resistance. One of the least understood areas in the environmental risk assessment of genetically modified crops is their impact on soil- and plant-associated microbial communities. The potential for interaction between transgenic plants and plant residues and the soil microbia...

In nature, living organisms are constantly producing different macromolecules for their metabolic needs. These macromolecules, such as polysaccharides, polynucleotides, proteins, or polyesters, are essential to organism survival. Their synthesis generally involves in vivo enzyme-catalyzed chaingrowth polymerization reactions of activated monomers, which are generally formed within the cells by ...

In nature microorganisms live in complex microbial communities. Comprehensive taxonomic and functional knowledge about microbial communities supports medical and technical application such as fecal diagnostics as well as operation of biogas plants or waste water treatment plants. Furthermore, microbial communities are crucial for the global carbon and nitrogen cycle in soil and in the ocean. Am...