Time-dependent density functional theory (TDDFT) has been applied to study core excitations from 1s and 2p Mn orbitals in a series of manganese complexes with oxygen and nitrogen donor ligands. The effect of basis set and functional on the excitation energy was evaluated in detail for one complex, Mn(acac)2 x (H2O)2. The results obtained for a range of compounds, namely, [Mn(Im)6]Cl2, Mn(CH3COO...

Microorganisms catalyze the formation of naturally occurring Mn oxides, but little is known about the biochemical mechanisms of this important biogeochemical process. We used tandem mass spectrometry to directly analyze the Mn(II)-oxidizing enzyme from marine Bacillus spores, identified as an Mn oxide band with an in-gel activity assay. Nine distinct peptides recovered from the Mn oxide band of...

In the present study, two experiments were conducted to investigate the effect of Mn source on Mn transport and the expression of a Mn transporter, divalent metal transporter 1 (DMT1), in the small intestine of broilers. In Expt 1, in situ ligated duodenal loops from Mn-deficient chicks (29-d-old) were perfused with solutions containing 0-8.74 mmol Mn/l from either MnSO4, or one of two organic ...

A catalytic manganese (Mn) cluster is required for the oxidation of water in the oxygen-evolving complex (OEC) of photosystem II (PSII) in plants. Despite this essential role of Mn in generating the electrons driving photosynthesis, limited information is available on how Mn deficiency affects PSII functionality. We have here used parameters derived from measurements of fluorescence induction k...

Iron (Fe) and manganese (Mn) are essential nutrients for plants. Application of high levels of either Fe or Mn is often accompanied by relatively low levels of uptake for the other nutrient. The antagonistic relationship of these nutrient elements may occur either during absorption by roots or during translocation from roots to shoot. A greenhouse study was carried out to study the effect of so...

Manganese (Mn) toxicity in crops is a serious problem in Hawaii, especially Kauai and Oahu, where most soils are highly weathered. To devise a management strategy to control Mn toxicity, a greenhouse experiment was conducted on an acid (pH 4.4) Oxisol (Wahiawa series) having 15g·kg total Mn. Factorial combinations of lime (0, 2.0, and 4.0 g·kg CaCO3) and two composts (made from chicken manure a...

Manganese (Mn) is a required element and a metabolic byproduct of the contrast agent mangafodipir trisodium (MnDPDP). The Mn released from MnDPDP is initially sequestered by the liver for first-pass elimination, which allows an enhanced contrast for diagnostic imaging. The administration of intravenous Mn impacts its homeostatic balance in the human body and can lead to toxicity. Human Mn defic...

Management of Staphylococcus aureus Bacteremia Bharath Raj Palraj, MBBS; Larry M. Baddour, MD; Erik Hess, MD; James Steckelberg, MD; Walter R. Wilson, MD; Brian Lahr, MS; Muhammad R. Sohail, MD; Department of Medicine, Division of Infectious Diseases, Mayo Clinic, Rochester, MN; Division of Infectious Diseases, Mayo Clinic, Rochester, MN; Department of Emergency Medicine, Mayo Clinic, Rochester...

The concurrent antineutrophil cytoplasmic antibody-associated glomerulonephritis (ANCA-GN) and membranous nephropathy (MN) have been increasingly documented, mainly in case studies and case series; however, the differences of clinical and pathologic characteristics as well as outcomes between ANCA-GN patients with and without MN remain unclear. The current study investigated the clinical and im...

Manganese (Mn) is an essential micronutrient for development and function of the nervous system. Deficiencies in Mn transport have been implicated in the pathogenesis of Huntington's disease (HD), an autosomal dominant neurodegenerative disorder characterized by loss of medium spiny neurons of the striatum. Brain Mn levels are highest in striatum and other basal ganglia structures, the most sen...