Objective: To analyze the expression of glutaminase 1 (GLS1) gene in breast cancer and its clinical significance in neoadjuvant chemotherapy. Methods: A total of 134 female patients with breast cancer who were treated in Department of Thyroid and Breast Surgery, Nanjing Drum Tower Hospital were selected. After being diagnosed by biopsy, they were randomly divided into two groups (n=67). Before ...

A 44-year-old woman presented with marked erythema over right mastectomy scar, while on Herceptin therapy. She had neoadjuvant chemotherapy, modified radical mastectomy, and radiotherapy less than one year earlier for the treatment of invasive ductal carcinoma. On physical examination, no palpable masses were detected in the erythematous skin. A biopsy revealed permeation of the skin lymphatics...

Objectives: To compare the modified radical mastectomy with breast conservative surgery in term of recurrence cancer. Material and methods: Between April 2021 to October 2021, total 60 women having age 30 years were selected from Department Surgery, D.G Khan Hospital, Kahn. Type study was randomized controlled trial. Recurrence rate cancer compared between both groups. Results: Mean 43.83 ± 9.6...

Primary neuroendocrine carcinoma of the breast (NECB) is an extremely rare variant of breast cancer having aggressive clinicopathological behaviour and poor prognosis. A 62 years old woman presented with a painless lump in the left breast. Microscopic and immunohistochemical evaluation of the core-tissue biopsy and of the mastectomy specimen revealed moderately-differentiated neuroendocrine car...

UNLABELLED The aim of this study is to emphasize the importance of knowing the predisposing factors of the occurrence of homolateral upper limb lymphedema after breast cancer surgery. MATERIAL AND METHODS The study included 1104 patients with breast cancer, who were hospitalized in the IIIrd Surgical Clinic, lasi, between 2000 and 2010, for surgical treatment followed by oncological adjuvant ...

A randomized trial was conducted at the Institut Gustave-Roussy (IGR) between 1972 and 1980 comparing tumorectomy and breast irradiation with modified radical mastectomy. One hundred and seventy-nine patients with an infiltrating breast carcinoma up to 20 mm in diameter at macroscopic examination were included: 88 had conservative management, and 91 a mastectomy. All patients had a low-axillary...

The aim of this study was to compare the morbidity, mortality, oncological results and quality of life between laparoscopic radical cystectomy (LRC) and open radical cystectomy (ORC) in the elderly patients over 75 years old. Between January 2012 and January 2015, 60 patients were recruited into this study, who were randomly assigned in a 1:1 ratio to either LRC or ORC group. Baseline patient c...