1Third Department of Internal Medicine, Japanese Red Cross Nagasaki Genbaku Hospital, Nagasaki; 2Department of Molecular Medicine and Hematology, Molecular Medicine Unit, Atomic Bomb Disease Institute, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki; 3Department of Nutritional Health, Faculty of Wellness Studies, Kwassui Women’s College, Nagasaki; 4Division of Cytokine Sign...

Inherited or acquired impairment of xenobiotics metabolism is a postulated mechanism underlying environment-associated pathologies such as multiple chemical sensitivity, fibromyalgia, chronic fatigue syndrome, dental amalgam disease, and others, also collectively named idiopathic environmental intolerances (IEI). In view of the poor current knowledge of their etiology and pathogenesis, and the ...

In 1964, when the European Molecular Biology Organization (EMBO) was founded, molecular biology was a small, emerging field within the biological sciences. The founders of EMBO, among them name just a few, belonged to the avant-garde of molecular biology. They came from different backgrounds—physics, chemistry, medicine and biology, but they shared interest in two basic questions: (i) What are ...

We focus on themes that are derived from clinical practice and research in the field of genetic diseases of bone and inborn errors of metabolism but may be of more general interest as they indicate some trends in molecular medicine as related to pediatrics. Identifying the disease-causing mechanism brings about efficient therapeutic strategies and discovering the mutant genotype in the near fut...

Background: Advancement in science and technology is one of the axioms of the general policies stated by the Supreme Leader of the Islamic Republic of Iran. Along with the Development and Innovation Program in Medical Education, Birjand University of Medical Sciences, as one of the country’s higher education institutions in healthcare, has identified its peculiar potentials for...

1Max-Delbrück-Center for Molecular Medicine, Berlin, Germany; 2Institute of Pathology, Charité-Universitätsmedizin Berlin, Berlin, Germany; 3Leeds Institute for Molecular Medicine, University of Leeds, Leeds, United Kingdom; 4Department of Cellular and Molecular Medicine, Hubrecht Institute, KNAW, and University Medical Center, Utrecht, The Netherlands; and 5University of California–San Diego, ...

1P PENG, MD, 2Z H ZHU, MD, 1Z J ZHONG, MD, 2K ZHENG, MD, 1J X YANG, MD, 1D Y CAO, MD and 1K SHEN, MD Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China Department of Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical C...

Comparison Between the Inside-outand Outside-in Techniques Masahito Yoshida, Hideyuki Goto, MD, PhD, Masahiro Nozaki, MD, PhD, Yasuhiro Nishimori, Atsunori Murase, Tetsuya Takenaga, MD, Yuko Nagaya, Masaaki Kobayashi, MD, PhD, Takanobu Otsuka. Nagoya City University, Graduate School of Medical Science Nagoya, Nagoya, Japan, Nagoya City University, Graduate School of Medical Science, Nagoya, Jap...

Restriction enzymes have proved to be invaluable for the physical mapping of DNA. They offer unparalleled opportunities for diagnosing DNA sequence content and are used in fields as disparate as criminal forensics and basic research. In fact, without restriction enzymes, the biotechnology industry would certainly not have flourished as it has. The first experiments demonstrating the utility of ...

During the recent decades, substantial changes are made in the borders and contents of physiology as a basic course for the students in medicine. Here some strategies are presented to preserve the classical and integrative approaches in teaching physiology, while these approaches extent our knowledge to molecular, sub-cellular and cellular levels.