Distillers grains, a coproduct of ethanol production from cereal grains, are composed principally of the bran, protein, and germ fractions and are commonly supplemented in ruminant diets. The objective of this study was to assess the effect of feeding wet distillers grains with solubles (WDGS) and monensin and tylosin on the prevalence and antimicrobial susceptibilities of fecal foodborne and c...

The role of the Golgi complex in the intracellular transport of influenza virus haemagglutinin in infected MDCK cell monolayers has been investigated using monensin, a carboxylic ionophore known to disrupt the functioning of this organelle in other cell types. In untreated cells metabolically labelled 5 h post-infection with [35S]methionine haemagglutinin was first seen in core glycosylated for...

The objective of this study was to determine the effects of garlic oil (Allium sativa), turmeric powder (Curcuma longa Linn) and Monensin on Total apparent digestibility of nutrients in Baloochi lambs. The experiment was designed as a 4 x 4 Latin square using 4 ruminally baloochi lambs with 4 treatments in four 28-d periods. Treatments were control (no additive), garlic oil (0. 4 g/d), monensin...

Two ionophores (monensin and gramicidin) that carry Na+ into 3T3 cells markedly enhance the rate of 86Rb+ uptake. Ouabain prevents both ionophores from increasing 86Rb+ uptake, indicating that the ionophores activate the Na+,K+ pump. Measurements of 86Rb+ uptake and cell Na+ and K+ over a range of monensin concentrations show that the activity of the Na+,K+ pump in 3T3 cells is limited by the s...

Corn dried distillers grains with solubles (DDGS) contains high crude fat and is reported to confer to PUFA some degree of protection from ruminal biohydrogenation (BH). There is also indication that inclusion in diets of high energy feed such as DDGS results in a reduced response to monensin in feedlot cattle. This study was conducted to determine the effects of increasing corn DDGS inclusion ...

The dynamics of different ionic currents shape the bursting activity of neurons and networks that control motor output. Despite being ubiquitous in all animal cells, the contribution of the Na(+)/K(+) pump current to such bursting activity has not been well studied. We used monensin, a Na(+)/H(+) antiporter, to examine the role of the pump on the bursting activity of oscillator heart interneuro...

The efficiency of feedstuff utilization by ruminal microorganisms and the cow’s genetic ability to convert feed nutrients into milk and milk components are major factors that influence the profitability of a dairy herd. Monensin’s ability to modify the movement of ions across biological membranes leads to alterations in bacterial populations and subsequent changes in the proportion of volatile ...

Monensin (1), a carboxylic polyether antibiotic has been extensively used as an anticoccidial agent for poultry1} and to improve the efficiency of feed utilization in ruminant' animals2^. Despite the considerable economic and environmental implications of this extensive use in animals, few data are available on the detoxification processes of such molecules. Wedescribed recently the bioconversi...

Five trials in five locations in the United States involving 512 steers were conducted to evaluate the effect of monensin [200 mg/d in .9 kg of supplement (Ru mensin )] and estradiol-controlled release implants ( Compudose ) administered alone and in combination on average daily gain (ADG) in steers on pasture. The effect of energy supplementation on rate of gain was also evaluated in these sam...