To explore the possibility that the analysis of autonomic reflexes could identify subgroups at high risk of ventricular fibrillation, we studied chronically instrumented mongrel dogs randomly divided into two groups. Twelve dogs served as controls and 17 were studied 3-4 weeks after anterior wall myocardial infarction (MI). After recovery, the dogs were given bolus i.v. injections of phenylephr...

Adult mongrel dogs were given a lethal dose of E. Coli endotoxin by rapid intravenous injection. Total serotonin levels in the serum fell rapidly, with the concentration in the portal vein and pulmonary artery significantly exceeding that in the femoral artery within the first minute after injection. Small rises in plasma serotonin were found in some of the animals. These changes were coinciden...

A mongrel male dog of three years old was referred to the Seoul National University Veterinary Teaching Hospital following a one month history of glaucoma. On ophthalmic examination, hyphema, glaucoma, uveitis, iridal mass, and loss of vision were noted in the right eye. Ultrasonography and computed tomography revealed a mass with involvement of the entire uvea. Radiographic evaluation did not ...

The study on the antioxidant and hypolipidemic effect of pollen extracts (Cernitins) was conducted in male mongrel rabbits and Wistar rats. The animals were fed a high-fat diet (HFD) composed of cholesterol, coconut oil and cholic acid, and received pollen extracts (Cernitins) orally (the rabbits over a period of 12 weeks and the rats over a period of 2 weeks). The levels of malondialdehyde (MD...

Our purpose was to determine whether prolonged myocardial ischemia attenuates free radical production after early reperfusion. Twenty-two mongrel dogs underwent left anterior descending coronary artery occlusion for 20, 40, or 60 minutes followed by 30 minutes of reperfusion. Electron paramagnetic resonance spectroscopy was used to measure ascorbate free radical in the coronary vein effluent. A...

Phonation was induced in 10 mongrel dogs under general anesthesia by way of transtracheal stimulation of the recurrent laryngeal nerves under conditions of constant air flow. Although stimulation voltages were approximately 10 times the voltage required for direct stimulation, no cardiac or respiratory abnormalities were observed. Photoglottographic and electroglottographic signals were the sam...

In 7 open-chest anesthetized mongrel dogs the left anterior descending coronary artery was occluded for 20 sec. Myocardial reactive hyperemia was recorded during air and oxygen breathings. The excess blood flow during the reactive hyperemia was smaller and the duration of the reactive hyperemia was shorter during oxygen breathing than during air breathing. It is suggested that the reduction of ...

1. Simultaneous thoracic duct and hepatic lymph flows were measured in 29 mongrel dogs before and after the intravenous administration of mannitol, ethacrynic acid, frusemide and chlorothiazide in separate experiments. 2. Thoracic duct lymph flow increased significantly after each diuretic agent was administered. 3. Hepatic lymph flow increased only after ethacrynic acid and mannitol administra...

Salivary gland tumors are uncommon in domestic animals, whereas salivary carcinosarcomas are very rare in the dog. A 15-year-old mongrel bitch was diagnosed with carcinosarcoma of the submandibular salivary gland extending into the adjacent muscular tissues and the jugular vein. The tumor displayed two distinct areas, one portion with sarcomatous neoplastic cells with bone and cartilage differe...