The spectroscopy and photo-induced dissociation of flavin mononucleotide anions in vacuo are investigated over the 300–500 nm wavelength range. Comparison dependence fragment ion yields as a function deposited photon energy with calculated energies collision-induced measurements performed under single-collision conditions suggests that substantial fraction photo-activated ions decompose through...

Nicotinamide mononucleotide (NMN) is a key precursor of nicotinamide adenine dinucleotide and an important source cellular energy. It can prevent neuronal mitochondrial defects alleviate heart fibrosis. Strategies to improve NMN production have implications for human health. Through plasmid expression technology CRISPR/Cas9 technology, we engineered Escherichia coli efficient production. First,...

We report here a method to manipulate the amount of thiolated DNA attached per gold nanoparticle from a few to tens of strands in less than an hour, which involves the tuning of the respective amount of salt and time of addition of thiolated oligo(ethylene glycol) during mononucleotide-mediated conjugation process.