Commentary Systemic sclerosis is one of the rheumatic diseases that is associated with the worst prognosis. Systemic sclerosis is divided into localized and systemic forms. Localized scleroderma comprises four subtypes, namely morphea, generalized morphea, linear scleroderma and en coup de saber, and is more commonly encountered in children. Although conversion into systemic sclerosis is very u...

intense the granular deposits, the slower and more persistent the course of the disease, whereas a diffuse pattern of pigmentation with an absence of globules or dots was associated with earlier resolution.9,10 In our patient we observed a mottled pattern formed by clusters of numerous brown dots and globules and, as predicted, the course clinical was slow and the condition persisted for a year...

To the Editor: Generalized morphea (GM) is a rare subtype of localized scleroderma characterized by widespread involvement. GM defined presence at least 4 lesions larger than 3 cm that involve 2 anatomic sites.1Laxer R.M. Zulian F. Localized scleroderma.Curr Opin Rheumatol. 2006; 18: 606-613Crossref PubMed Scopus (243) Google Scholar Isomorphic and symmetric subsets were recently delineated bas...

HSV: herpes simplex virus SCC: squamous cell carcinoma INTRODUCTION Metastatic disease to the skin can be difficult to diagnose clinically because it often mimics many infectious, inflammatory, and neoplastic skin conditions. Cutaneousmetastases can present as dermal or subcutaneous nodules, exophytic tumors resembling melanoma or nonmelanoma skin cancer, erythematous patches and plaques resemb...

Hepatitis C virus has been associated with various skin conditions, such as porphyria cutanea tarda and lichen planus, as an example. The objective of this paper is based on the description of a case of localized morphea, which came years after the discovery of hepatitis C, as well as a discussion of possible relations between both diseases.