Nanomaterial-based carrier systems hold great promise to deliver therapies with increased efficacy and reduced side effects. While the state-of-the-art carrier system is a sphere, recent data indicate that elongated rods and filaments have advantageous flow and margination properties, resulting in enhanced vascular targeting and tumor homing. Here, we report on the distinct diffusion rates of t...

Thermal denaturation of RNA free coat proteins of tobacco mosaic virus (TMV) was studied for wildtype TMV (vulgare) and the temperature-sensitive mutant, Ni 118. The ability to form soluble aggregates as well as the optical properties (ORD, UV-difference spectra), and the sedimen­ tation behavior were used as criteria for the native state. At pH 7.5 , 7 = 0 .0 2 denaturation is reversible for b...

The paper proposes a new image mosaic algorithm based on relative orientation. In view of image registration errors in existing image mosaic algorithms, the relative orientation method is introduced. The parameters of relative orientation are obtained by parsing stereo image pairs, and the transformation model of ideal image pairs are generated. The paper uses mean parallax method to register t...

OBJECTIVES Mosaic autosomal duplications are rare and often result in mental retardation and congenital anomalies. Phenotype is not predictable depending on the chromosomal imbalance involved and the percentage and tissues distribution of unbalanced cells. We report on a young woman carrying a mosaic duplication of chromosome 4p, evaluated because of three abortions due to IUGR and fetal malfor...

In a previous book (Chapouthier, 2001), one of the authors developed a thesis describing living beings by using the metaphor of the mosaic. A mosaic, as a work of art, is a representation, either figurative or abstract, and the perception of the total image as a whole is the result of the juxtaposition of small coloured elements, and their subsequent integration when perceived visually, but wit...