esophageal melanocytosis is a rare and benign condition, characterized by melanocytic proliferation of the esophageal squamous epithelium with heavy melanin deposition. the etiology and pathogenesis has not been exactly known but it seems to be a chronic stimulus such as gastroesophageal reflux. this condition is very rare and about 35 cases have been reported so far, most of which have been fr...

conclusions we conclude that oral cancer is etiologically related to the interaction between smoking and drinking. results the smoking as well as alcohol drinking rates in the subjects of the case group were significantly higher than the controls. of smoking types, bidi (a hand rolled cigarette) (or = 4.1, 95% ci = 2.4-6.9), and among alcohol types, hard liquor (or = 2.6, 95% ci = 1. 4-6.4), cou...

The objective of this study was to compare unstimulated salivary flow rate and residual salivary volume (the volume of saliva retained in the mouth after swallowing) in a group of 23 control subjects and a group of 25 patients who had received radiation treatment or had undergone removal of the salivary glands (or both) for head and neck cancer. As expected, the mean flow rate (+/- 0 standard d...

BACKGROUND The aim of this prospective study was to determine whether a level of positive airway pressure was generated in participants receiving nasal high flow (NHF) delivered by the Optiflow system (Fisher and Paykel Healthcare Ltd, Auckland, New Zealand) in a cardiothoracic and vascular intensive care unit (ICU). METHODS Nasopharyngeal airway pressure was measured in 15 postoperative card...

Measurement of exhaled nitric oxide (NO) may allow noninvasive assessment of inflammatory disease in the lung. We determined immediate and day-to-day reproducibility of single-breath NO measurements at different points on the exhaled test, and whether levels recorded reflect levels of NO in the lower airways. Using a rapid chemiluminescence analyser, 55 healthy control subjects performed three ...

BACKGROUND AND OBJECTIVE Goal was to evaluate the potential of in vivo optical coherence tomography (OCT) imaging to determine the response of patients with xerostomia to a dry mouth toothpaste versus fluoride toothpaste placebo. STUDY DESIGN/MATERIALS AND METHODS Ten subjects with xerostomia participated in this double-blind, crossover, placebo-controlled study. After examination and OCT ima...

Integrative research at the interphase between ecology, developmental, and evolutionary biology increasingly highlights the importance of phenotypic plasticity, the property of a single genotype to produce different phenotypes depending on environmental conditions. Plasticity occurs in multiple forms at the morphological, physiological, and behavioral levels. It can be reversible or irreversibl...

The ability to internally simulate other persons' actions is important for social interaction. In monkeys, neurons in the premotor cortex are activated both when the monkey performs mouth or hand actions and when it views or listens to actions made by others. Neuronal circuits with similar "mirror-neuron" properties probably exist in the human Broca's area and primary motor cortex. Viewing othe...

OBJECTIVE The objective of this study was to compare an image-guided puncture technique (IGPT) with conventional puncture technique (CPT) with respect to accuracy of needle entry, maximal mouth opening, and pain in pumping manipulation treatment of internal derangement of the temporomandibular joint (TMJ). STUDY DESIGN The subjects comprised 178 patients with internal derangement of the TMJ w...

INTRODUCTION Despite tobacco control and health promotion efforts, the incidence rates of mouth cancer are increasing across most regions in India. Analysing the influence of age, time period and birth cohort on these secular trends can point towards underlying factors and help identify high-risk populations for improved cancer control programmes. METHODS We evaluated secular changes in mouth...