Mechanically interlocked and entangled molecular architectures represent one of the elaborate topological superstructures engineered at a molecular resolution. Here we report a methodology for fabricating mechanically selflocked molecules (MSMs) through highly efficient one-step amidation of a pseudorotaxane derived from dual functionalized pillar[5]arene (P[5]A) threaded by α,ω-diaminoalkane (...

Substantial literature has been devoted to supply chain coordination. The majority of this literature ignores competition between supply chains. Moreover, a significant part of this literature focuses on coordination that induce the supply chain members to follow strategies that produce the equilibria chosen by a vertically integrated supply chain. This paper investigates the equilibrium behavi...

A thorough analysis of the protein interaction partners of the yeast GTPase Gsp1p was carried out by a multidimensional chromatography strategy of strong cation exchange fractionation of peptides followed by reverse phase LC-ESI-MSMS using a QSTAR instrument. This dataset was then analyzed using the latest developmental version of Protein Prospector. The Prospector search results were also comp...

The allure of a molecular dynamics simulation is that, given a sufficiently accurate force field, it can provide an atomic-level view of many interesting phenomena in biology. However, the result of a simulation is a large, high-dimensional time series that is difficult to interpret. Recent work has introduced the time-structure based Independent Components Analysis (tICA) method for analyzing ...

We discuss why it is not always obvious how to simulate longitudinal data from a general marginal structural model (MSM) for a survival outcome while ensuring that the data exhibit complications due to time-dependent confounding. On the basis of the relation between a directed acyclic graph and an MSM, we suggest a data-generating process that satisfies both these requirements, the general vali...

The effect of spray drying on the different polyphenolic compounds present in root a purple-fleshed sweet potato variety Ipomoea batatas native from Peru was performed by HPLC-QTOF-MSMS. Nine anthocyanins, including four peonidin, three cyanidin and two pelargonidin derivatives glycosylated with sophorose and/or glucose acylated caffeic, ferulic p-hydroxybenzoic acid were identified. Twenty nin...

Background: Sexual and gender minorities all over the world are heavily impacted by attitudes beliefs of those around them. With this study, researcher is trying to explore impact Section 377 (2018 judgment) on relationships between Men who have Sex with (MSM) their parents. Method: This qualitative study was completed using semi-structured interviews that were conducted 11 MSM living in Delhi ...

During 2009 there was an increased incidence of acute hepatitis A virus (HAV) infection among homosexual males which, in our institute, outnumbered the number of cases in travellers, thus becoming the prime HAV risk factor. Some of our HAV cases occurred in HIV-infected subjects. This observation underlines the action of HAV as a sexually transmitted infection and urges preventive measures, suc...