Both superantigens (SAG) and many anti-TCR monoclonal antibodies (mAb) have specificity for the V beta region of the TCR encoded by TCRBV genes. For instance the bacterial SAG staphylococcal enterotoxin E (SEE), the retroviral SAG MTV-9 and the mAb OT145 each react with human T cells expressing BV6S7. This BV gene encodes two common alleles. We found that SEE and the mAb preferentially activate...

The results of learning physical education skills were not limited to development but also mental and motivation learn. purpose this study was determine the effect block method (BM) play-based random (RM) on long jump (JLS) in terms (MTV). This type research is quasi-experimental with a 2x2 factorial design. A sample 20 Samiun Makassar public primary school students randomly selected divided in...

Gel mobility shift analysis using P-labeled DNA probes is a powerful and fast method to analyse sequence-specific DNA-binding proteins, mainly transcription and enhancer factors. We routinely use this method to determine the quality of purified steroid hormone receptors, namely the rat glucocorticoid receptor and the rabbit progesterone receptor, with regard to DNA-binding. To overcome the vari...

We apply the formulation of a stochastic mode reduction method developed in a recent paper of Majda, Timofeyev, and Vanden-Eijnden [Comm. Pure Appl. Math., 54 (2001), pp. 891– 974] (MTV) to obtain simplified equations for the dynamics of structures immersed in a thermally fluctuating fluid at low Reynolds (or Kubo) number, as simulated by a recent extension of the immersed boundary (IB) method ...

The stable subdivision of Drosophila limbs into anterior and posterior compartments is a consequence of asymmetrical signalling by Hedgehog (Hh), from the posterior to anterior cells. The activity of the homeodomain protein Engrailed in posterior cells helps to generate this asymmetry by inducing the expression of Hh in the posterior compartment and, at the same time, repressing the expression ...

To investigate whether superantigen (SAG) from endogenous mouse mammary tumor virus functions as an immunogenic or a tumorigenic factor in tumor development, the BALB/c myeloma cell line FO was transfected with the SAG gene from the 3' Mtv-50 long terminal repeat (LTR) open reading frame (ORF), the product of which was specific for Vbeta6. All five transfectants expressing Mtv-50 LTR ORF mRNA s...

The murine Mls-1 antigen is the prototype of endogenous superantigens, molecules whose activities lead to deletion of T cells expressing certain T-cell receptor V beta genes from the mature repertoire. However, Mls-1 also stimulates T cells expressing these particular V beta genes (V beta 6, V beta 7, V beta 8.1, and V beta 9) in vitro, making it one of the strongest known T-cell activators. We...

Activated glucocorticoid receptor protein, purified to 40-60% homogeneity from rat liver extracts, binds selectively in vitro to a cloned fragment of murine mammary tumor virus (MTV) DNA. The DNA fragment tested contains about half of the sequences present in intact MTV DNA, and its rate of transcription, like that of the intact viral element, is strongly stimulated by glucocorticoids when it i...

BACKGROUND Non-Hodgkin's lymphomas arising from the tissues other than primary lymphatic organs are named primary extranodal lymphoma. Most of the studies evaluated metabolic tumor parameters in different organs and histopathologic variants of this disease generally for treatment response. We aimed to evaluate the prognostic value of metabolic tumor parameters derived from initial FDG-PET/CT in...

BACKGROUND The inflammatory reactions are stronger after surgery of malnourished preoperative patients. Many studies have shown vitamin and trace element deficiencies appear to affect the functioning of immune cells. Enteral nutrition is often inadequate for malnourished patients. Therefore, total parenteral nutrition (TPN) is considered an effective method for providing preoperative nutritiona...