BACKGROUND There is a paucity of data on the prevalence of multifocal primary hyperhidrosis and changes in hyperhidrosis severity over time. OBJECTIVE The goal of this study was to better understand multifocal primary hyperhidrosis, prevalence and distribution of hyperhidrosis by focal site, age of onset of symptoms by focal area, and change in hyperhidrosis severity over time and with season...

UNLABELLED INTRODUCTION The majority of multifocal micronodular pneumocyte hyperplasia associated with tuberous sclerosis complex is diagnosed with the classical clinical triad of seizures, mental retardation, and skin lesions. We report a rare case of tuberous sclerosis complex with no classical clinical findings, which was diagnosed through incidental computed tomography findings of multip...

fMRI is becoming an important clinical tool for planning and guidance of surgery to treat brain tumors, arteriovenous malformations, and epileptic foci. For visual cortex mapping, the most popular paradigm by far is temporal phase mapping, although random multifocal stimulation paradigms have drawn increased attention due to their ability to identify complex response fields and their random pro...

BACKGROUNDS/AIMS Appropriate management for multifocal branch duct type intraductal papillary mucinous neoplasms (BD-IPMNs) of the pancreas is still controversial. This study was intended to reveal surgical outcomes of surgical resection for multifocal BD-IPMNs, with BD-IPMNs in the remnant pancreas. METHODS Between January 1995 and December 2013, 699 patients underwent the pancreatic resecti...

Widespread mammography and the increasing use of breast-conserving therapy make bilateral and multifocal breast cancer more important issues in patient care. The biologic mechanisms of these two cancer types differ. Bilateral breast cancer results from independent primaries in the two breasts, while multifocal breast cancer can result from either intramammary spread from a single index tumor or...

The aim of this study was to compare the visual performance of Acrysof ReSTOR and Acrysof Natural intraocular lenses (IOLs) following cataract surgery. A randomized prospective study was performed in which 64 eyes (51 patients) were divided randomly into two groups. Monofocal IOLs (Acrysof Natural) were implanted into 34 eyes (27 patients) and multifocal IOLs (Acrysof ReSTOR) were implanted int...

Prostate cancer is widely observed to be biologically heterogeneous. Its heterogeneity is manifested histologically as multifocal prostate cancer, which is observed more frequently than unifocal prostate cancer. The clinical and prognostic significance of either focal cancer type is not fully established. To investigate prostate cancer heterogeneity, the genetic profiles of multifocal and unifo...

PURPOSE To assess the impact of blue-light filtering on retinal processing to evaluate potential side effects of these filters on visual function at the neural level. SETTING Department of Ophthalmology, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany. DESIGN Cohort study. METHODS Multifocal electroretinograms (ERGs) were recorded monocularly after pupil dilation in pseudophaki...

One case of recurrent multifocal central giant cell granulomas (CGCG) is presented. Initially, the lesions presented concurrently in the maxilla and mandible with subsequent recurrence in the mandible. Now, two recurrences are seen in the maxillary sinus and ethmoid region. The literature regarding multifocal CGCG is reviewed.

We read with great interest a recently published article by Lecoutere et al [1] entitled “multifocal cytokeratin expression in pleural and abdominal malignant solitary fibrous tumor: an unusual diagnostic pitfall”. Authors showed three histologically and immunohistochemically welldocumented cases of pleural and abdominal malignant solitary fibrous tumor (SFT) with unexpected multifocal expressi...