A 72-year-old male underwent neck dissection and parotidectomy with facial nerve preservation. Endotracheal intubation was facilitated with succinylcholine. Prolonged muscle paralysis which was first detected after failure to stimulate the facial nerve with electrocautery, lasted five hours. Laboratory tests indicated pseudocholinesterase (PChE) deficiency. A thyroidectomy one month later was p...

Release of substance P (SP) from sensory nerve endings of the tracheobronchial system modulates airway smooth muscle contraction and may cause relaxation of precontracted airways. We sought to elucidate the effect of postnatal maturation on SP-induced relaxation of precontracted airways and determine the roles of endogenously generated nitric oxide (NO) and prostaglandins (PGs). Cylindrical air...

1. Four 3-alkylxanthines (3-methylxanthine, 3-n-propylxanthine (enprofylline), 3-n-butylxanthine and 3-iso-butylxanthine) and four 1-methyl-3-alkylxanthines (1-methyl-3-methylxanthine (theophylline), 1-methyl-3-n-propylxanthine, 1-methyl-3-n-butylxanthine and 1-methyl-3-iso-butylxanthine (IBMX], were compared in terms of cyclic AMP phosphodiesterase (PDE) inhibition and trachealis muscle relaxa...

Papaverine, a nonspecific smooth muscle relaxant, is well known to be a potent cyclic AMP phosphodiesterase inhibitor (1, 2). In recent papers (3-8) it has been reported that smooth muscle relaxing action of papaverine is likely to be mediated through an increase of cyclic AMP due to its phosphodiesterase inhibition. Recently attention has drawn to the role of cyclic GMP, which often presents p...

In the last few years, the growth of l-day surgery and the introduction of new techniques have increased the need for general anesthesia with endotracheal intubation and mechanical ventilation. The end point of l-day anesthesia is early patient discharge home. Therefore, new muscle relaxant agents have been propounded to anesthetists to achieve this. In this paper, we analyze pharmacological an...

Hypothesis / aims of study Urtica dioica (commonly known as stinging nettle) is used worldwide as an alternative to conventional pharmacotherapies for benign prostatic hyperplasia (BPH). The root extract is commonly used in Europe, primarily in Germany, for the treatment of the symptoms associated with BPH. It is thought to alleviate lower urinary tract symptoms (LUTS) by reducing stromal proli...

OBJECTIVE To determine the effects of resveratrol on the ileal smooth muscle reactivity in polymicrobial sepsis. MATERIAL AND METHODS Polimicrobial sepsis was induced by the cecal ligation and perforation (CLP) procedure. Sprague Dawley rats were divided into three groups. Rats in resveratrol group received resveratrol after CLP (100 mg/kg, i.p.). Rats received saline immediately after CLP in...

A - 7 month old female etawa belongs to Mr. Joko It shows that has problems of difficulties opening it's mouth and soundless for three days. The physical check is carried out through palpalis from goat's nails, legs, in the area. result checks found goat could not open got pain while touching it. In area scars. indicates spesial tetanus., this was diagnosed with tetanus, where characteristic sy...

The review presents the results of clinical studies efficacy and safety Tenoten children’s in treatment anxiety, neurotic, stress-related somatoform disorders adjustment disorders. Technologically processed antibodies to S100 protein drugs change conformation protein, which is considered as a pathological link development anxiety states, well neurodegenerative diseases. well-studied daytime anx...