PURPOSE To compare the virulence of wild-type Candida albicans strains in a murine model of corneal candidiasis and to investigate the role of fungal filamentation in disease progression. METHODS Scarified corneas of immunocompetent or cyclophosphamide-treated BALB/c mice were topically inoculated with one of three human isolates of C. albicans, a homozygous mutant of the pH-dependent filamen...

In the present study, Streptomyces gulbargensis and its mutant form, S.gulbargensis mu24, immobilized on polyurethane foam were investigated for the production of L-asparaginase using groundnut cake extract as medium. The medium with an initial pH of 8.5 was inoculated with free and immobilized cells separately and then subjected to fermentation by incubation at 40oC and shaking at 200 rev/min....

there is no functional annotation for the majority of the several hundreds of receptor-like kinases in plants. a direct way of inferring the function of these proteins is to study the phenotype that results from loss of function mutants such as t-dna mutant lines. in this research a function (phenotype) to at2g37050 gene that encodes a receptor like kinase in arabidopsis t-dna line was assigned...