Abstract The roles extracellular polymeric substances (EPS) play in mineral attachment and weathering were studied using genetically modified biofilms of the rock-inhabiting fungus Knufia petricola strain A95. Mutants deficient melanin and/or carotenoid synthesis grown as air-exposed biofilms. Extracted EPS quantified characterised a combination analytical techniques. absence affected quantity ...

In the present work we studied the birth order in progenies of lranian survivors of Iraqi chemical attacks during a period from 1984 to 1989. Then we compared the results with the birth order of the control group. Despite a slight difference between the birth order in the two groups of progenies, this was not statistically significant. This does not mean, however, that there are no genetic ...

background antibiotic resistance is a major therapeutic problem in patients infected with helicobacter pylori. h. pylori clarithromycin resistant mutants have been evolved during antibiotic therapy, this is mainly due to 23s rrna point mutations. objectives in the present study, we investigated anti-mutational features of four traditionally iranian medicinal plants on three local isolated h. py...

In the present study, selected rice (Oryza sativa cv. indica) was genetically modified to increase amylose content in seeds. The ‘CRISPR-Cas9’ genome-editing tool used knock out three isoforms of soluble starch synthase (SSS) viz. SSSII-1, SSSII-2 and SSSII-3. A genetic transformation vector designed with appropriate gRNAs, Cas9, antibiotic resistance create SSS knockout mutants enrich amylose....

Pancreatic ductal adenocarcinoma (PDAC) is among the world's deadliest cancers. Multiple studies demonstrated that PDAC frequently characterized by presence of Kirsten Rat Sarcoma (KRAS) G12D, G12V, and G12R protein mutants. The mutants are potential immunotherapy targets due to their as cancer-specific neoantigens. KRAS G12V contain vaccine-immunogenic epitopes. epitopes were presented at majo...

Plumbago indica L. is a perennial herb with ornamental and anticancer medicinal functions widely distributed in the tropics. It affected by temperature cannot bloom normally colder subtropical regions, which seriously affects its value. To create low-temperature resistance mutants enrich new germplasm resources, this study used tissue culture chemical reagent (0.5 mmol/L NaN 3 ) stress (0°C, fu...

conclusions our results demonstrated no significant correlation between the ird5 lifespan and the trehalose concentration. likewise, the correlation between lifespan extension, trehalose accumulation, and cellular resistance to hydrogen peroxide was not significant. results the lifespan of the ird5 mutant was significantly longer that of either the ird11 mutant or the wild type cells. under rep...

Citrus canker, caused by the bacterium Xanthomonas citri (Xcc), is one of most devastating diseases for citrus industry. Xylose a constituent cell wall plants, and ability Xcc to use this carbohydrate may play role in virulence. has two genes codifying xylose isomerase (XI), bifunctional enzyme that interconverts D-xylose into D-xylulose D-glucose D-fructose. The aim work was investigate functi...