Moldy grain may adversely affect cattle production due to nutrition effects, mycoses or mycotoxicoses. Mycosis is a disease state caused by the fungi themselves, and mycotoxicosis is a disease state caused by secondary metabolites of the fungi. Thus, the mold itself may cause production losses separate and apart from any toxin effects. In fact, various molds have been associated with adverse he...

Fungal infections of the eye are an important cause of significant visual loss and blindness in some regions of the world, especially developing countries. Ocular mycoses remain a diagnostic and therapeutic challenge to the ophthalmologist. Corneal infection is the most frequent presentation, but the orbit, eyelids, lacrimal apparatus, conjunctiva, sclera and internal structures of the eye can ...

Many fungi are now emerging as important causes of superficial and deep seated infections man. The indiscriminate use broad spectrum antimicrobials by oral topical routes prolonged hospital stay have led to emergence many new fungal pathogens like Candida auris, Histoplasma spp. Emergomyces spp.. Of these, C. auris is an established nosocomial pathogen can colonize surfaces very commonly. Immun...

Evidence from several in vitro and animal model studies suggests a modulatory role of haemopoietic, T(H)1 and T(H)2 cytokines in host defence against fungi, and highlights their potential utility as adjunctive therapy for management of systemic mycoses (SM). However, there are limited clinical data to support the use of cytokines in prevention and treatment of SM. Thus, at present no adjunctive...

Moldy grain may adversely affect cattle production due to nutrition effects, mycoses or mycotoxicoses. Mycosis is a disease state caused by the fungi themselves, and mycotoxicosis is a disease state caused by secondary metabolites of the fungi. Thus, the mold itself may cause production losses separate and apart from any toxin effects. In fact, various molds have been associated with adverse he...

The incidence of mycotic infections in the CNS has increased even outside those groups of patients with increased risk (AIDS, drug-addicts, etc.). These cases are secondary complications of other basic diseases favored by the influence of modern drug treatment and misinterpretation of modern diagnostic findings (radiology). A more frequent control of mycotic infections even in routine controls ...

Introduction Compared to antibacterial drugs, antimicrobial agents available for treatment of invasive fungal infections are sparse. Amphotericin B (polyene) was the first drug introduced in the 1950s, followed by flucytosine (pyrimidine) in the 1970s, and first-generations azoles (fluconazole, itraconazole) in the 1990s. Triazoles (voriconazole, posaconalzole) and echinocandins (caspofungin, m...